[Term]
id: PR:Q8I4B0-6
name: potassium voltage-gated channel protein shk-1 isoform f (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-6." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:f (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-6
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-7
name: potassium voltage-gated channel protein shk-1 isoform g (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-7." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:g (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-7
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-4
name: potassium voltage-gated channel protein shk-1 isoform a (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-4." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-4
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-5
name: potassium voltage-gated channel protein shk-1 isoform e (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-5." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:e (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-5
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-2
name: potassium voltage-gated channel protein shk-1 isoform b (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-2." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-2
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-3
name: potassium voltage-gated channel protein shk-1 isoform d (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-3." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:d (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-3
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8I4B0-1
name: potassium voltage-gated channel protein shk-1 isoform c (worm)
def: "A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-1." [PRO:DNx, UniProtKB:Q8I4B0]
comment: Category=organism-sequence.
synonym: "KCNA2/iso:c (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0-1
is_a: PR:Q8I4B0 ! potassium voltage-gated channel protein shk-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:P16389
name: potassium voltage-gated channel subfamily A member 2 (human)
def: "A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "KCNA2" RELATED Gene-based [UniProtKB:P16389]
synonym: "hKCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "NGK1 (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated K(+) channel HuKIV (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated potassium channel HBK5 (human)" EXACT [UniProtKB:P16389]
synonym: "voltage-gated potassium channel subunit Kv1.2 (human)" EXACT [UniProtKB:P16389]
xref: Reactome:R-HSA-977477 "PR:P16389 located_in GO:0005886"
xref: DTO:01100181
xref: UniProtKB:P16389
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000810 ! voltage-gated potassium channel subunit KCNA2
relationship: has_gene_template HGNC:6220 ! KCNA2 (human)

[Term]
id: PR:P63142-1
name: potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "rKCNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63142-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000972 ! voltage-gated potassium channel subunit KCNA2 isoform 1

[Term]
id: PR:P63142
name: potassium voltage-gated channel subfamily A member 2 (rat)
def: "A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of rat." [OMA:P63142, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kcna2" RELATED Gene-based [UniProtKB:P63142]
synonym: "rKCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "RAK (rat)" EXACT [UniProtKB:P63142]
synonym: "RBK2 (rat)" EXACT [UniProtKB:P63142]
synonym: "RCK5 (rat)" EXACT [UniProtKB:P63142]
synonym: "voltage-gated potassium channel subunit Kv1.2 (rat)" EXACT [UniProtKB:P63142]
xref: UniProtKB:P63142
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000810 ! voltage-gated potassium channel subunit KCNA2
relationship: has_gene_template RGD:2950 ! Kcna2 (rat)

[Term]
id: PR:P63141
name: potassium voltage-gated channel subfamily A member 2 (mouse)
def: "A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of mouse." [OMA:P63141, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kcna2" RELATED Gene-based [UniProtKB:P63141]
synonym: "mKCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "MK2 (mouse)" RELATED [UniProtKB:P63141]
synonym: "voltage-gated potassium channel subunit Kv1.2 (mouse)" EXACT [UniProtKB:P63141]
xref: UniProtKB:P63141
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000810 ! voltage-gated potassium channel subunit KCNA2
relationship: has_gene_template MGI:96659 ! Kcna2 (mouse)

[Term]
id: PR:000001001
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the pair of Ser residues within the SSPD motif at the C terminus. Phosphorylation at this site promotes cell surface localization. Example: UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633]
comment: Category=modification.
synonym: "KCNA2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000991 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000001000
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the REDEGYIK sequence located adjacent to the tetramerization domain. Phosphorylation at this site promotes endocytosis and suppresses the channel activity. Example: UniProtKB:P16389-1, Tyr-132, MOD:00048." [PRO:CNA]
comment: Category=modification.
synonym: "KCNA2/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000991 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:P63141-1
name: potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mKCNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63141-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000972 ! voltage-gated potassium channel subunit KCNA2 isoform 1

[Term]
id: PR:000000991
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "KCNA2/iso:1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000000972 ! voltage-gated potassium channel subunit KCNA2 isoform 1

[Term]
id: PR:Q8I4B0
name: potassium voltage-gated channel protein shk-1 (worm)
def: "A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of worm." [OMA:Q8I4B0, PRO:DNx]
comment: Category=organism-gene.
synonym: "shk-1" RELATED Gene-based [UniProtKB:Q8I4B0]
synonym: "ZK1321.2" RELATED Gene-based [UniProtKB:Q8I4B0]
synonym: "KCNA2 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8I4B0
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000000810 ! voltage-gated potassium channel subunit KCNA2
relationship: has_gene_template WormBase:WBGene00014261 ! shk-1 (worm)

[Term]
id: PR:000036584
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNA2/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16389-1, Tyr-132, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001000 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000036585
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in mouse. UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "mKCNA2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001001 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000036586
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in rat. UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "rKCNA2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000001001 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000036587
name: voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]
comment: Category=organism-modification.
synonym: "hKCNA2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001001 ! voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000000810
name: voltage-gated potassium channel subunit KCNA2
def: "A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits." [PMID:16382104]
comment: Category=gene.
synonym: "MK2" RELATED []
synonym: "NGK1" EXACT []
synonym: "KCNA2" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated K(+) channel HuKIV" EXACT []
synonym: "voltage-gated potassium channel HBK5" EXACT []
synonym: "voltage-gated potassium channel subunit Kv1.2" EXACT []
xref: IUPHARobj:539
is_a: PR:000000709 ! shaker-related voltage-gated potassium channel alpha subunit

[Term]
id: PR:000000972
name: voltage-gated potassium channel subunit KCNA2 isoform 1
def: "A voltage-gated potassium channel subunit KCNA2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16389-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "KCNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000810 ! voltage-gated potassium channel subunit KCNA2

[Term]
id: PR:P16389-1
name: potassium voltage-gated channel subfamily A member 2 isoform 1 (human)
def: "A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hKCNA2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16389-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000972 ! voltage-gated potassium channel subunit KCNA2 isoform 1

[Term]
id: PR:P16389-2
name: potassium voltage-gated channel subfamily A member 2 isoform h2 (human)
def: "A potassium voltage-gated channel subfamily A member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16389-2." [PRO:DNx, UniProtKB:P16389]
comment: Category=organism-sequence.
synonym: "hKCNA2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16389-2
is_a: PR:P16389 ! potassium voltage-gated channel subfamily A member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens