[Term]
id: PR:P22459
name: potassium voltage-gated channel subfamily A member 4 (human)
def: "A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "KCNA4" RELATED Gene-based [UniProtKB:P22459]
synonym: "KCNA4L" RELATED Gene-based [UniProtKB:P22459]
synonym: "hKCNA4" EXACT PRO-short-label [PRO:DNx]
synonym: "HPCN2 (human)" EXACT [UniProtKB:P22459]
synonym: "voltage-gated K(+) channel HuKII (human)" EXACT [UniProtKB:P22459]
synonym: "voltage-gated potassium channel HK1 (human)" EXACT [UniProtKB:P22459]
synonym: "voltage-gated potassium channel HBK4 (human)" EXACT [UniProtKB:P22459]
synonym: "voltage-gated potassium channel subunit Kv1.4 (human)" EXACT [UniProtKB:P22459]
xref: Reactome:R-HSA-977474 "PR:P22459 located_in GO:0005886"
xref: DTO:01100183
xref: UniProtKB:P22459
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000683 ! voltage-gated potassium channel alpha subunit KCNA4
relationship: has_gene_template HGNC:6222 ! KCNA4 (human)

[Term]
id: PR:000000683
name: voltage-gated potassium channel alpha subunit KCNA4
def: "A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA4 gene or a 1:1 ortholog thereof. The Kv1.4 channel is a fast-inactivating channel involved in neuronal after hypolarization. It can coassemble with other Kv1 subunits. It is closely related to members of the shaker-related voltage-gated potassium channel, but has a unique N-terminal domain, with two tandem inactivation domains (ID1-ID2). ID1 may work as a pore-occluding ball domain, whereas ID2 most likely acts as a docking domain that attaches ID1 to the cytoplasmic face of the channel." [PMID:12590144]
comment: Category=gene.
synonym: "HPCN2" EXACT []
synonym: "KCNA4" EXACT PRO-short-label [PRO:DNx]
synonym: "KCNA4L" RELATED Gene-based []
synonym: "voltage-gated K(+) channel HuKII" EXACT []
synonym: "voltage-gated potassium channel HK1" EXACT []
synonym: "voltage-gated potassium channel HBK4" EXACT []
synonym: "voltage-gated potassium channel subunit Kv1.4" EXACT []
xref: IUPHARobj:541
xref: PIRSF:PIRSF038521
is_a: PR:000000685 ! voltage-gated potassium channel alpha subunit