[Term] id: PR:000000417 name: activin/inhibin beta B chain isoform 1 def: "An activin/inhibin beta B chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09529-1 or a 1:1 ortholog thereof." [PMID:15319829, PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "INHBB/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000217 ! activin/inhibin beta B chain [Term] id: PR:000000638 name: activin/inhibin beta B chain isoform 1 cleaved 1 def: "An activin/inhibin beta B chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide, yielding the mature protein. It is a subunit of activin B, inhibin B and activin AB complexes. Activin B is a homodimer of INHBB. Inhibin B is a dimer of INHA and INHBB. Activin AB is a dimer of INHBA and INHBB." [PMID:3754442] comment: Category=modification. synonym: "INHBB/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000021912 ! activin/inhibin beta B chain isoform 1, signal peptide removed form intersection_of: lacks_part SO:0001062 ! propeptide [Term] id: PR:P09529-1 name: inhibin beta B chain isoform 1 (human) def: "An activin/inhibin beta B chain isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09529] comment: Category=organism-sequence. synonym: "hINHBB/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P09529-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000417 ! activin/inhibin beta B chain isoform 1 [Term] id: PR:Q04999 name: inhibin beta B chain (mouse) def: "An activin/inhibin beta B chain that is encoded in the genome of mouse." [OMA:Q04999, PRO:DNx] comment: Category=organism-gene. synonym: "Inhbb" RELATED Gene-based [UniProtKB:Q04999] synonym: "mINHBB" EXACT PRO-short-label [PRO:DNx] synonym: "activin beta-B chain (mouse)" EXACT [UniProtKB:Q04999] xref: UniProtKB:Q04999 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000217 ! activin/inhibin beta B chain relationship: has_gene_template MGI:96571 ! Inhbb (mouse) [Term] id: PR:P27093 name: inhibin beta B chain (chicken) def: "An activin/inhibin beta B chain that is encoded in the genome of chicken." [OMA:P27093, PRO:DNx] comment: Category=organism-gene. synonym: "INHBB" RELATED Gene-based [UniProtKB:P27093] synonym: "chick-INHBB" EXACT PRO-short-label [PRO:DNx] synonym: "activin beta-B chain (chicken)" EXACT [UniProtKB:P27093] xref: UniProtKB:P27093 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000000217 ! activin/inhibin beta B chain relationship: has_gene_template NCBIGene:396126 ! INHBB (chicken) [Term] id: PR:000021912 name: activin/inhibin beta B chain isoform 1, signal peptide removed form def: "An activin/inhibin beta B chain isoform 1 that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "INHBB/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000000417 ! activin/inhibin beta B chain isoform 1 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000000217 name: activin/inhibin beta B chain def: "An activin/inhibin beta subunit that is a translation product of the human INHBB gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "INHBB" EXACT PRO-short-label [PRO:DNx] synonym: "activin beta-B chain" EXACT [] xref: PANTHER:PTHR11848:SF29 is_a: PR:000000072 ! activin/inhibin beta subunit [Term] id: PR:P17491 name: inhibin beta B chain (rat) def: "An activin/inhibin beta B chain that is encoded in the genome of rat." [OMA:P17491, PANTHER:PTHR11848:SF29, PRO:DNx] comment: Category=organism-gene. synonym: "Inhbb" RELATED Gene-based [UniProtKB:P17491] synonym: "rINHBB" EXACT PRO-short-label [PRO:DNx] synonym: "activin beta-B chain (rat)" EXACT [UniProtKB:P17491] xref: UniProtKB:P17491 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000000217 ! activin/inhibin beta B chain relationship: has_gene_template RGD:2913 ! Inhbb (rat) [Term] id: PR:000054651 name: inhibin beta B chain O-glycosylated 1 (human) def: "An inhibin beta B chain (human) that has been O-glycosylated at the residue equivalent to Ser-47 of the amino acid sequence represented by UniProtKB:P09529-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P09529-1, Ser-47, MOD:00002~GNO:G43417UB." [GlyGen:P09529-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hINHBB/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P09529-1, Ser-47, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P09529 ! inhibin beta B chain (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000054652 name: inhibin beta B chain O-glycosylated 2 (human) def: "An inhibin beta B chain (human) that has been O-glycosylated at the residue equivalent to Thr-35 of the amino acid sequence represented by UniProtKB:P09529-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P09529-1, Thr-35, MOD:00005~GNO:G43417UB." [GlyGen:P09529-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hINHBB/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P09529-1, Thr-35, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P09529 ! inhibin beta B chain (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P09529 name: inhibin beta B chain (human) def: "An activin/inhibin beta B chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P09529] comment: Category=organism-gene. synonym: "INHBB" RELATED Gene-based [UniProtKB:P09529] synonym: "hINHBB" EXACT PRO-short-label [PRO:DNx] synonym: "activin beta-B chain (human)" EXACT [UniProtKB:P09529] xref: UniProtKB:P09529 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000217 ! activin/inhibin beta B chain relationship: has_gene_template HGNC:6067 ! INHBB (human) [Term] id: PR:000036541 name: activin/inhibin beta B chain isoform 1 cleaved 1 (human) def: "An activin/inhibin beta B chain isoform 1 cleaved 1 in human. UniProtKB:P09529-1, 293-407." [PMID:10320815, PMID:2575216, PMID:3122219, PMID:3754442, PRO:CNA] comment: Category=organism-modification. synonym: "PRO_0000033723" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hINHBB/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P09529-1, 293-407" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1449664 "PR:000036541 located_in GO:0005576" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000638 ! activin/inhibin beta B chain isoform 1 cleaved 1 [Term] id: PR:000021927 name: activin/inhibin beta B chain proteolytic cleavage product def: "An activin/inhibin beta B chain that has been processed by proteolytic cleavage." [PRO:DAN] comment: Category=modification. synonym: "INHBB/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000000217 ! activin/inhibin beta B chain [Term] id: PR:Q04999-1 name: inhibin beta B chain isoform 1 (mouse) def: "An activin/inhibin beta B chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q04999] comment: Category=organism-sequence. synonym: "mINHBB/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q04999-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000417 ! activin/inhibin beta B chain isoform 1