[Term] id: PR:P27038-1 name: activin receptor type-2A isoform 1 (mouse) def: "An activin receptor type-2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P27038] comment: Category=organism-sequence. synonym: "mACVR2A/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P27038-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000208 ! activin receptor type-2A isoform 1 [Term] id: PR:000000528 name: activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 def: "An activin receptor type-2A isoform 1 glycosylated and phosphorylated form in which the phosphorylation occurs at Ser/Thr residues. This constitutes the active receptor subunit." [PMID:8395525] comment: Category=modification. synonym: "ACVR2A/iso:1/GlycoPhos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000414 ! activin receptor type-2A isoform 1 glycosylated and phosphorylated form relationship: has_part MOD:00693 ! glycosylated residue relationship: has_part MOD:00696 ! phosphorylated residue [Term] id: PR:P38444 name: activin receptor type-2A (rat) def: "An activin receptor type-2A that is encoded in the genome of rat." [PANTHER:PTHR23255:SF10, PRO:DNx] comment: Category=organism-gene. synonym: "Acvr2" RELATED Gene-based [UniProtKB:P38444] synonym: "Actrii" RELATED Gene-based [UniProtKB:P38444] synonym: "Acvr2a" RELATED Gene-based [UniProtKB:P38444] synonym: "rACVR2A" EXACT PRO-short-label [PRO:DNx] synonym: "ACTR-IIA (rat)" EXACT [UniProtKB:P38444] synonym: "activin receptor type IIA (rat)" EXACT [UniProtKB:P38444] xref: UniProtKB:P38444 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000000070 ! activin receptor type-2A relationship: has_gene_template RGD:70911 ! Acvr2a (rat) [Term] id: PR:000000414 name: activin receptor type-2A isoform 1 glycosylated and phosphorylated form def: "An activin receptor type-2A isoform 1 that includes at least one glycosylated residue and at least one phosphorylated residue." [PRO:CNA] comment: Category=modification. synonym: "ACVR2A/iso:1/GlycoPhos+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00693 ! glycosylated residue intersection_of: has_part MOD:00696 ! phosphorylated residue intersection_of: PR:000000208 ! activin receptor type-2A isoform 1 [Term] id: PR:P27037-1 name: activin receptor type-2A isoform 1 (human) def: "An activin receptor type-2A isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27037] comment: Category=organism-sequence. synonym: "hACVR2A/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P27037-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000208 ! activin receptor type-2A isoform 1 [Term] id: PR:000000070 name: activin receptor type-2A def: "A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human ACVR2A gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "ACVR2" RELATED Gene-based [] synonym: "ACVR2A" EXACT PRO-short-label [PRO:DNx] synonym: "ACTRIIA" EXACT [] synonym: "ACTR-IIA" EXACT [] synonym: "activin receptor type IIA" EXACT [] xref: IUPHARobj:1791 xref: PIRSF:PIRSF500457 is_a: PR:000000007 ! TGF-beta superfamily receptor type-2 with activin receptor domain [Term] id: PR:P27037-2 name: activin receptor type-2A isoform h2 (human) def: "An activin receptor type-2A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27037-2." [PRO:DNx, UniProtKB:P27037] comment: Category=organism-sequence. synonym: "hACVR2A/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P27037-2 is_a: PR:P27037 ! activin receptor type-2A (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000208 name: activin receptor type-2A isoform 1 def: "An activin receptor type-2A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27038-1 or a 1:1 ortholog thereof." [PMID:8395525, PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "ACVR2A/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000070 ! activin receptor type-2A [Term] id: PR:P27038 name: activin receptor type-2A (mouse) def: "An activin receptor type-2A that is encoded in the genome of mouse." [OMA:P27038, PRO:DNx] comment: Category=organism-gene. synonym: "Acvr2" RELATED Gene-based [UniProtKB:P27038] synonym: "Acvr2a" RELATED Gene-based [UniProtKB:P27038] synonym: "mACVR2A" EXACT PRO-short-label [PRO:DNx] synonym: "ACTR-IIA (mouse)" EXACT [UniProtKB:P27038] synonym: "activin receptor type IIA (mouse)" EXACT [UniProtKB:P27038] xref: UniProtKB:P27038 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000070 ! activin receptor type-2A relationship: has_gene_template MGI:102806 ! Acvr2a (mouse) [Term] id: PR:000036441 name: activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human) def: "An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in human." [PMID:12665502, PMID:1314589, PMID:8622651, PRO:CNA] comment: Category=organism-modification. synonym: "hACVR2A/iso:1/GlycoPhos:1" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000528 ! activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 relationship: has_part MOD:00693 ! glycosylated residue relationship: has_part MOD:00696 ! phosphorylated residue [Term] id: PR:000036440 name: activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) def: "An activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 in mouse." [PMID:10452853, PMID:11459935, PMID:12414726, PMID:16991118, PMID:7885474, PMID:8395525, PMID:8612709, PRO:CNA] comment: Category=organism-modification. synonym: "mACVR2A/iso:1/GlycoPhos:1" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000528 ! activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 relationship: has_part MOD:00693 ! glycosylated residue relationship: has_part MOD:00696 ! phosphorylated residue [Term] id: PR:Q90669 name: activin receptor type-2A (chicken) def: "An activin receptor type-2A that is encoded in the genome of chicken." [OMA:Q90669, PRO:DNx] comment: Category=organism-gene. synonym: "ACVR2A" RELATED Gene-based [UniProtKB:Q90669] synonym: "chick-ACVR2A" EXACT PRO-short-label [PRO:DNx] synonym: "ACTRIIA (chicken)" EXACT [UniProtKB:Q90669] synonym: "ACTR-IIA (chicken)" EXACT [UniProtKB:Q90669] synonym: "activin receptor type IIA (chicken)" EXACT [UniProtKB:Q90669] xref: UniProtKB:Q90669 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000000070 ! activin receptor type-2A relationship: has_gene_template NCBIGene:396324 ! ACVR2A (chicken) [Term] id: PR:000046258 name: activin receptor type-2A, signal peptide removed form (human) def: "An activin receptor type-2A (human) that has had the signal peptide removed. UniProtKB:P27037, 20-513." [PRO:DNx, Reactome:R-HSA-201659] comment: Category=organism-modification. synonym: "PRO_0000024398" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hACVR2A/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P27037, 20-513" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-201659 "PR:000046258 located_in GO:0005886" intersection_of: PR:P27037 ! activin receptor type-2A (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P27037 name: activin receptor type-2A (human) def: "An activin receptor type-2A that is encoded in the genome of human." [PRO:CNA, UniProtKB:P27037] comment: Category=organism-gene. synonym: "ACVR2" RELATED Gene-based [UniProtKB:P27037] synonym: "ACVR2A" RELATED Gene-based [UniProtKB:P27037] synonym: "hACVR2A" EXACT PRO-short-label [PRO:DNx] synonym: "ACTRIIA (human)" EXACT [UniProtKB:P27037] synonym: "ACTR-IIA (human)" EXACT [UniProtKB:P27037] synonym: "activin receptor type IIA (human)" EXACT [UniProtKB:P27037] xref: DTO:03100038 xref: UniProtKB:P27037 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000070 ! activin receptor type-2A relationship: has_gene_template HGNC:173 ! ACVR2A (human)