Protein Ontology Report - mHSPH1 PR:Q61699 - http://purl.obolibrary.org/obo/PR_Q61699

This page represents a class of proteins encompassing all the protein products of the HSPH1 gene in mouse .

Ontology Information
PRO ID	PR:Q61699 Show OBO stanza / PAF
PRO name	heat shock protein 105 kDa (mouse)
Synonyms	PRO-short-label: mHSPH1 EXACT: 42 degrees C-HSP (mouse); HSP-E7I (mouse); heat shock 110 kDa protein (mouse); heat shock-related 100 kDa protein E7I (mouse) Gene-based: Hsp105; Hsp110; Hsph1; Kiaa0201
Definition	A heat shock protein 105 kDa that is encoded in the genome of mouse. [OMA:Q61699, PRO:DAN]
PRO Category	organism-gene
Parent	PR:000003410 heat shock protein 105 kDa
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	MGI:105053, UniProtKB:Q61699

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q61699-2 mHSPH1/iso:HSP105-beta located_in GO:0005634 nucleus MGI:5607133, PMID:17643418 located_in GO:0005634 nucleus MGI:4422145, PMID:19754877 located_in GO:0005634 nucleus MGI:5607132, PMID:19028714 participates_in GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI:3688933, PMID:16857185 participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4422145, PMID:19754877 participates_in GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI:3822965, PMID:18681888 participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:5607132, PMID:19028714 participates_in GO:1903753 negative regulation of p38MAPK cascade MGI:3822965, PMID:18681888 participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4422145, PMID:19754877 participates_in GO:2001234 negative regulation of apoptotic signaling pathway MGI:3688933, PMID:16857185 participates_in GO:0061098 positive regulation of protein tyrosine kinase activity MGI:4422145, PMID:19754877 PR:Q61699-1 mHSPH1/iso:HSP105-alpha located_in GO:0005737 cytoplasm MGI:5607133, PMID:17643418 participates_in GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI:3688933, PMID:16857185 participates_in GO:2001234 negative regulation of apoptotic signaling pathway MGI:3688933, PMID:16857185 participates_in GO:1903753 negative regulation of p38MAPK cascade MGI:3822965, PMID:18681888 participates_in GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI:3822965, PMID:18681888 Biological Process GO Term Protein Forms & Complexes Evidence GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide PR:Q61699-1 mHSPH1/iso:HSP105-alpha MGI:3822965, PMID:18681888 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:3822965, PMID:18681888 GO:2001234 negative regulation of apoptotic signaling pathway PR:Q61699-1 mHSPH1/iso:HSP105-alpha MGI:3688933, PMID:16857185 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:3688933, PMID:16857185 GO:1903748 negative regulation of establishment of protein localization to mitochondrion PR:Q61699-1 mHSPH1/iso:HSP105-alpha MGI:3688933, PMID:16857185 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:3688933, PMID:16857185 GO:0061098 positive regulation of protein tyrosine kinase activity PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:4422145, PMID:19754877 GO:1903753 negative regulation of p38MAPK cascade PR:Q61699-1 mHSPH1/iso:HSP105-alpha MGI:3822965, PMID:18681888 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:3822965, PMID:18681888 GO:0045944 positive regulation of transcription by RNA polymerase II PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:4422145, PMID:19754877 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:5607132, PMID:19028714 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:4422145, PMID:19754877 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:5607133, PMID:17643418 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:4422145, PMID:19754877 PR:Q61699-2 mHSPH1/iso:HSP105-beta MGI:5607132, PMID:19028714 GO:0005737 cytoplasm PR:Q61699-1 mHSPH1/iso:HSP105-alpha MGI:5607133, PMID:17643418

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