Protein Ontology Report - hIKBKG PR:Q9Y6K9 - http://purl.obolibrary.org/obo/PR_Q9Y6K9

This page represents a class of proteins encompassing all the protein products of the IKBKG gene in human .

Ontology Information
PRO ID	PR:Q9Y6K9 Show OBO stanza / PAF
PRO name	NF-kappa-B essential modulator (human)
Synonyms	PRO-short-label: hIKBKG EXACT: FIP-3 (human); I-kappa-B kinase subunit gamma (human); IKK-gamma (human); IKKAP1 (human); IKKG (human); IkB kinase subunit gamma (human); IkB kinase-associated protein 1 (human); NF-kappa-B essential modifier (human); inhibitor of nuclear factor kappa-B kinase subunit gamma (human) Gene-based: FIP3; IKBKG; NEMO
Definition	An NF-kappa-B essential modulator that is encoded in the genome of human. [PRO:DNx]
PRO Category	organism-gene
Parent	PR:000001752 NF-kappa-B essential modulator
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100364, HGNC:5961, Reactome:R-HSA-1168576, Reactome:R-HSA-168108, Reactome:R-HSA-4755413, UniProtKB:Q9Y6K9

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hIKBKG forms found in complexes
hIKBKG Component Complexes PR:Q9Y6K9 hIKBKG PR:000026457 IkappaB kinase complex (human) PR:Q9Y6K9 hIKBKG PR:000035833 activated IkappaB kinase complex (human) PR:Q9Y6K9 hIKBKG PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) PR:Q9Y6K9 hIKBKG PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 participates_in GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 PR:000026457 IkappaB kinase complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_26016 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 PR:000035833 activated IkappaB kinase complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 Biological Process GO Term Protein Forms & Complexes Evidence GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_6809 PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 GO:0034142 toll-like receptor 4 signaling pathway PR:000026457 IkappaB kinase complex (human) Reactome:REACT_6894 PR:000035833 activated IkappaB kinase complex (human) Reactome:REACT_6894 GO:0034138 toll-like receptor 3 signaling pathway PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0010008 endosome membrane PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_26016 PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) Reactome:REACT_6783

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