Protein Ontology Report - hRIPK3 PR:Q9Y572 - http://purl.obolibrary.org/obo/PR_Q9Y572

This page represents a class of proteins encompassing all the protein products of the RIPK3 gene in human .

Ontology Information
PRO ID	PR:Q9Y572 Show OBO stanza / PAF
PRO name	receptor-interacting serine/threonine-protein kinase 3 (human)
Synonyms	PRO-short-label: hRIPK3 EXACT: RIP-3 (human); RIP-like protein kinase 3 (human); receptor-interacting protein 3 (human) Gene-based: RIP3; RIPK3
Definition	A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human. [PRO:CNA, Reactome:R-HSA-450328]
PRO Category	organism-gene
Parent	PR:000014024 receptor-interacting serine/threonine-protein kinase 3
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100452, HGNC:10021, Reactome:R-HSA-450328, UniProtKB:Q9Y572

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hRIPK3 forms found in complexes
hRIPK3 Component Complexes PR:Q9Y572 hRIPK3 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) PR:Q9Y572 hRIPK3 PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) PR:Q9Y572 hRIPK3 PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) PR:Q9Y572 hRIPK3 PR:000037332 rip3:ticam1:activated TLR3 complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_152149 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_151344 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 PR:000037332 rip3:ticam1:activated TLR3 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 participates_in GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 PR:Q9Y572 hRIPK3 located_in GO:0005737 cytoplasm Reactome:REACT_22021 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 participates_in GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 Biological Process GO Term Protein Forms & Complexes Evidence GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_6809 PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_6809 PR:000037332 rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 GO:0034138 toll-like receptor 3 signaling pathway PR:000037332 rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005737 cytoplasm PR:Q9Y572 hRIPK3 Reactome:REACT_22021 GO:0010008 endosome membrane PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_152149 PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) Reactome:REACT_151344 PR:000037332 rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) Reactome:REACT_6783

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