Protein Ontology Report - hKNL1 PR:Q8NG31 - http://purl.obolibrary.org/obo/PR_Q8NG31

This page represents a class of proteins encompassing all the protein products of the KNL1 gene in human .

Ontology Information
PRO ID	PR:Q8NG31 Show OBO stanza / PAF
PRO name	kinetochore scaffold 1 (human)
Synonyms	PRO-short-label: hKNL1 EXACT: AF15q14 (human); ALL1-fused gene from chromosome 15q14 protein (human); Bub-linking kinetochore protein (human); CT29 (human); blinkin (human); cancer susceptibility candidate gene 5 protein (human); cancer/testis antigen 29 (human); kinetochore-null protein 1 (human); protein CASC5 (human); protein D40/AF15q14 (human) Gene-based: CASC5; KIAA1570; KNL1
Definition	A kinetochore scaffold 1 that is encoded in the genome of human. [PMID:20624902, PRO:KER]
PRO Category	organism-gene
Parent	PR:000005050 kinetochore scaffold 1
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 4 organism-modification 2
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	HGNC:24054, Reactome:R-HSA-375322, Reactome:R-HSA-606296, UniProtKB:Q8NG31

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035558 hKNL1/iso:2/Phos:1 Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046 participates_in GO:0034501 protein localization to kinetochore increased relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415 PR:Q8NG31 hKNL1 capable_of GO:0005515 protein binding with PR:O43683 hBUB1 BioGRID:BG-723200 capable_of GO:0005515 protein binding with PR:O14777 hNDC80 BioGRID:BG-723196 capable_of GO:0005515 protein binding with PR:O60566 hBUB1B BioGRID:BG-697221 located_in GO:0000776 kinetochore PMID:20624902 Biological Process GO Term Protein Forms & Complexes Evidence GO:0034501 protein localization to kinetochore PR:000035558 hKNL1/iso:2/Phos:1 Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046 increased relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000776 kinetochore PR:Q8NG31 hKNL1 PMID:20624902

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