Protein Ontology Report - chick-TLR4 PR:Q7ZTG5 - http://purl.obolibrary.org/obo/PR_Q7ZTG5

This page represents a class of proteins encompassing all the protein products of the TLR4 gene in chicken .

Ontology Information
PRO ID	PR:Q7ZTG5 Show OBO stanza / PAF
PRO name	Toll-like receptor 4 (chicken)
Synonyms	PRO-short-label: chick-TLR4 EXACT: chTLR4
Definition	A Toll-like receptor 4 that is encoded in the genome of chicken. [PMID:18768894, PMID:20483729, PRO:CNA]
PRO Category	organism-gene
Parent	PR:000001155 Toll-like receptor 4
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 0 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	CGNC:5282, Reactome:R-GGA-433970, UniProtKB:Q7ZTG5

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

chick-TLR4 forms found in complexes

chick-TLR4 Component Complexes PR:000001155 TLR4 PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex PR:000001155 TLR4 PR:000036003 LY96:TLR4 complex PR:000001155 TLR4 PR:000036076 activated TLR4 complex PR:000001155 TLR4 PR:000025784 MYD88:TIRAP:activated TLR4 receptor PR:Q7ZTG5 chick-TLR4 PR:000037473 LY96:TLR4 complex (chicken) PR:Q7ZTG5 chick-TLR4 PR:000037474 activated TLR4 complex (chicken) PR:Q7ZTG5 chick-TLR4 PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_26615 participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_25089 participates_in GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25089 PR:000037474 activated TLR4 complex (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_25442 participates_in GO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933 participates_in GO:0034142 toll-like receptor 4 signaling pathway PMID:18768894 participates_in GO:0051607 defense response to virus PMID:24034933 PR:000037473 LY96:TLR4 complex (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_26915 participates_in GO:0034142 toll-like receptor 4 signaling pathway PMID:18768894 participates_in NOT GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18768894 Biological Process GO Term Protein Forms & Complexes Evidence NOT GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000037473 LY96:TLR4 complex (chicken) PMID:18768894 GO:0002755 MyD88-dependent toll-like receptor signaling pathway PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) Reactome:REACT_25089 GO:0034142 toll-like receptor 4 signaling pathway PR:000037473 LY96:TLR4 complex (chicken) PMID:18768894 PR:000037474 activated TLR4 complex (chicken) PMID:18768894 PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) Reactome:REACT_25089 GO:0051607 defense response to virus PR:000037474 activated TLR4 complex (chicken) PMID:24034933 GO:0045429 positive regulation of nitric oxide biosynthetic process PR:000037474 activated TLR4 complex (chicken) PMID:24034933 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005886 plasma membrane PR:000037473 LY96:TLR4 complex (chicken) Reactome:REACT_26915 PR:000037474 activated TLR4 complex (chicken) Reactome:REACT_25442 PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) Reactome:REACT_26615

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