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Protein Ontology Report - mPSEN2/iso:PS2beta

PR:Q61144-2 - http://purl.obolibrary.org/obo/PR_Q61144-2
Ontology Information
PRO ID PR:Q61144-2 Show OBO stanza / PAF
PRO name presenilin-2 isoform PS2beta (mouse)
Synonyms
PRO-short-label: mPSEN2/iso:PS2beta
Definition A presenilin-2 isoform PS2beta that is encoded in the genome of mouse. The sequence is shorter (361 residues long) than isoform 1 sharing the same sequence up to residue 357, followed by the sequence SKGA. [PMID:19376115, PRO:KRC]
Comment Evidence=This isoform has been seen endogeneously in microsomal fraction from mouse brain.
PRO Category organism-sequence
Parent PR:000036853 presenilin-2 isoform PS2beta
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q61144-2
mPSEN2/iso:PS2beta
located_in GO:0005783 endoplasmic reticulum MGI:3843380, PMID:19376115
participates_in GO:0031333 negative regulation of protein-containing complex assembly MGI:3843380, PMID:19376115
participates_in GO:0032091 negative regulation of protein binding MGI:3843380, PMID:19376115
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031333 negative regulation of protein-containing complex assembly PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115
GO:0032091 negative regulation of protein binding PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005783 endoplasmic reticulum PR:Q61144-2 mPSEN2/iso:PS2beta

MGI:3843380, PMID:19376115

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