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Protein Ontology Report - hACVR2B

PR:Q13705 - http://purl.obolibrary.org/obo/PR_Q13705
This page represents a class of proteins encompassing all the protein products of the ACVR2B gene in human .
Ontology Information
PRO ID PR:Q13705 Show OBO stanza / PAF
PRO name activin receptor type-2B (human)
Synonyms
PRO-short-label: hACVR2B
EXACT: ACTR-IIB (human); activin receptor type IIB (human)
Gene-based: ACVR2B
Definition An activin receptor type-2B that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q13705]
PRO Category organism-gene
Parent PR:000000071 activin receptor type-2B
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 4
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000215
hACVR2B/var:V494I
Val-494, CHEBI:30009 		associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:9916847
PR:000000214
hACVR2B/var:R40H
Arg-40, CHEBI:29979 		associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:9916847
PR:000036443
hACVR2B/iso:ActR-IIB2/NGlycoPhos:1
capable_of GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8622651
capable_of GO:0005515 protein binding with PR:Q9UNH7 hSNX6 PMID:11279102, PMID:9872992
capable_of GO:0016362 activin receptor activity, type II PMID:8622651
located_in GO:0005887 integral component of plasma membrane PMID:8161782
part_of GO:0048179 activin receptor complex PMID:8622651
PR:Q13705-1
hACVR2B/iso:ActR-IIB2
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8161782
PR:Q13705-2
hACVR2B/iso:ActR-IIB1
capable_of NOT GO:0016362 activin receptor activity, type II PMID:9916847
has_agent SO:0001587 stop_gained PMID:9916847
PR:000000071
ACVR2B
capable_of GO:0048185 activin binding PIRSF:PIRSF500456
participates_in GO:0032924 activin receptor signaling pathway PIRSF:PIRSF500456
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:Q13705-1 hACVR2B/iso:ActR-IIB2

PMID:8161782
GO:0032924 activin receptor signaling pathway PR:000000071 ACVR2B

PIRSF:PIRSF500456
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005887 integral component of plasma membrane PR:000036443 hACVR2B/iso:ActR-IIB2/NGlycoPhos:1

PMID:8161782

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