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Protein Ontology Report - hKCNH2

PR:Q12809 - http://purl.obolibrary.org/obo/PR_Q12809
This page represents a class of proteins encompassing all the protein products of the KCNH2 gene in human .
Ontology Information
PRO ID PR:Q12809 Show OBO stanza / PAF
PRO name potassium voltage-gated channel subfamily H member 2 (human)
Synonyms
PRO-short-label: hKCNH2
EXACT: ERG-1 (human); Eag homolog (human); Eag-related protein 1 (human); H-ERG; ether-a-go-go-related gene potassium channel 1 (human); ether-a-go-go-related protein 1 (human); hERG-1; hERG1; voltage-gated potassium channel subunit Kv11.1 (human)
Gene-based: ERG; ERG1; HERG; KCNH2
Definition A voltage-gated potassium channel KCNH2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q12809]
PRO Category organism-gene
Parent PR:000000791 voltage-gated potassium channel KCNH2
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 6
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q12809
hKCNH2
participates_in GO:0006936 muscle contraction PMID:7736582
participates_in GO:0008016 regulation of heart contraction PMID:7736582
PR:000036583
hKCNH2/iso:A/Phos:1
capable_of GO:0005251 delayed rectifier potassium channel activity decreased relative to PR:000002666 KCNH2/iso:A/UnMod PMID:10837251
part_of GO:0008076 voltage-gated potassium channel complex PMID:10837251
PR:000045393
hKCNH2/iso:A/PhosRes-
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:10837251, PMID:9351446
PR:000045392
hKCNH2/iso:A/UnGlyco:1
Asn-598, PR:000026291 		located_in GO:0009986 cell surface PMID:12063277
PR:Q12809-1
hKCNH2/iso:A
capable_of GO:0030552 cAMP binding PMID:10837251
PR:000036581
hKCNH2/iso:A/NGlyco:1
Asn-598, MOD:00160 		located_in GO:0009986 cell surface PMID:12063277
part_of GO:0008076 voltage-gated potassium channel complex PMID:12063277
PR:Q12809-2
hKCNH2/iso:B
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:9351446
PR:Q12809-5
hKCNH2/iso:A-USO
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:9765245
part_of GO:0008076 voltage-gated potassium channel complex PMID:9765245
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008016 regulation of heart contraction PR:Q12809 hKCNH2

PMID:7736582
GO:0006936 muscle contraction PR:Q12809 hKCNH2

PMID:7736582
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:000036581 hKCNH2/iso:A/NGlyco:1
Asn-598, MOD:00160
PMID:12063277
PR:000045392 hKCNH2/iso:A/UnGlyco:1
Asn-598, PR:000026291
PMID:12063277

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