Protein Ontology Report - hACVR1 PR:Q04771 - http://purl.obolibrary.org/obo/PR_Q04771

This page represents a class of proteins encompassing all the protein products of the ACVR1 gene in human .

Ontology Information
PRO ID	PR:Q04771 Show OBO stanza / PAF
PRO name	activin receptor type-1 (human)
Synonyms	PRO-short-label: hACVR1 BROAD: TGF-B superfamily receptor type I (human); TSR-I (human) EXACT: ACTR-I (human); ALK-2 (human); SKR1 (human); activin receptor type I (human); activin receptor-like kinase 2 (human); serine/threonine-protein kinase receptor R1 (human) Gene-based: ACVR1; ACVRLK2
Definition	An activin receptor type-1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q04771]
Comment	Requested by=PubChem.
PRO Category	organism-gene
Parent	PR:000000067 activin receptor type-1
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100012, HGNC:171, UniProtKB:Q04771

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000000200 hACVR1/var:R206H Arg-206, CHEBI:29979 associated_with_disease_progression DOID:13374 fibrodysplasia ossificans progressiva PMID:8397373 located_in GO:0005887 integral component of plasma membrane PMID:8397373 PR:000036435 hACVR1/iso:1/SigPep-/Phos:1 capable_of GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8389764 capable_of GO:0048185 activin binding PMID:8242742 located_in GO:0005887 integral component of plasma membrane PMID:8242742, PMID:8397373 part_of GO:0048179 activin receptor complex PMID:8242742 participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8242742, PMID:8389764 Biological Process GO Term Protein Forms & Complexes Evidence GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742, PMID:8389764 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005887 integral component of plasma membrane PR:000000200 hACVR1/var:R206H Arg-206, CHEBI:29979 PMID:8397373 PR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742, PMID:8397373

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