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Protein Ontology Report - mSMAD4

PR:P97471 - http://purl.obolibrary.org/obo/PR_P97471
This page represents a class of proteins encompassing all the protein products of the SMAD4 gene in mouse .
Ontology Information
PRO ID PR:P97471 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 4 (mouse)
Synonyms
PRO-short-label: mSMAD4
EXACT: MAD homolog 4 (mouse); SMAD 4 (mouse); SMAD family member 4 (mouse); deletion target in pancreatic carcinoma 4 homolog (mouse); mothers against DPP homolog 4 (mouse)
Gene-based: Dpc4; Madh4; Smad4
Definition A smad4 that is encoded in the genome of mouse. [OMA:P97471, PRO:DNx]
PRO Category organism-gene
Parent PR:000000128 smad4
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSMAD4 forms found in complexes
mSMAD4 Component Complexes
PR:P97471-1 mSMAD4/iso:1 PR:000025944 smad2-smad4 protein complex 1 (mouse)
PR:P97471-1 mSMAD4/iso:1 PR:000025945 smad2-smad4 protein complex 2 (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025944
smad2-smad4 protein complex 1 (mouse)
located_in GO:0005634 nucleus PMID:12672795
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12672795
PR:P97471-1
mSMAD4/iso:1
capable_of GO:0003700 DNA-binding transcription factor activity PMID:12943993, PMID:14633973, PMID:16522160, PMID:16556916
located_in GO:0005634 nucleus PMID:12543979, PMID:12943993, PMID:16522160
part_of GO:0005667 transcription factor complex PMID:14633973, PMID:9288972, PMID:9702197
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17142805
participates_in GO:0030509 BMP signaling pathway PMID:16522160
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030509 BMP signaling pathway PR:P97471-1 mSMAD4/iso:1

PMID:16522160
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000025944 smad2-smad4 protein complex 1 (mouse)

PMID:12672795
PR:P97471-1 mSMAD4/iso:1

PMID:17142805
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025944 smad2-smad4 protein complex 1 (mouse)

PMID:12672795
PR:P97471-1 mSMAD4/iso:1

PMID:12543979, PMID:12943993, PMID:16522160

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