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Protein Ontology Report - hZFYVE9

PR:O95405 - http://purl.obolibrary.org/obo/PR_O95405
This page represents a class of proteins encompassing all the protein products of the ZFYVE9 gene in human .
Ontology Information
PRO ID PR:O95405 Show OBO stanza / PAF
PRO name zinc finger FYVE domain-containing protein 9 (human)
Synonyms
PRO-short-label: hZFYVE9
BROAD: NSP (human)
EXACT: Madh-interacting protein (human); hSARA; mothers against decapentaplegic homolog-interacting protein (human); novel serine protease (human); receptor activation anchor (human); smad anchor for receptor activation (human)
Gene-based: MADHIP; SARA; SMADIP; ZFYVE9
Definition A zinc finger FYVE domain-containing protein 9 that is encoded in the genome of human. [PRO:CNA]
PRO Category organism-gene
Parent PR:000000125 zinc finger FYVE domain-containing protein 9
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hZFYVE9 forms found in complexes
hZFYVE9 Component Complexes
PR:000000125 ZFYVE9 PR:000025974 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex
PR:O95405 hZFYVE9 PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:O95405-2
hZFYVE9/iso:2
located_in GO:0005615 extracellular space PMID:9582421
PR:O95405-3
hZFYVE9/iso:3
located_in GO:0005615 extracellular space PMID:9582421
PR:000000125
ZFYVE9
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PANTHER:PTHR22835:SF7
PR:O95405-1
hZFYVE9/iso:1
capable_of GO:0005515 protein binding with PR:P08100 hRHO PMID:17693260
capable_of GO:0005515 protein binding with PR:000025960 hSMAD2/iso:[Long/Short]/UnPhos:1 PMID:11877415, PMID:9865696
located_in GO:0005769 early endosome PMID:11877415, PMID:12356868, PMID:12432064
participates_in GO:0007183 SMAD protein complex assembly PMID:11877415, PMID:12356868
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10615055
participates_in GO:0006897 endocytosis PMID:12809483
participates_in GO:0060390 regulation of SMAD protein signal transduction PMID:11877415, PMID:12356868
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007183 SMAD protein complex assembly PR:O95405-1 hZFYVE9/iso:1

PMID:11877415, PMID:12356868
GO:0006897 endocytosis PR:O95405-1 hZFYVE9/iso:1

PMID:12809483
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:000000125 ZFYVE9

PANTHER:PTHR22835:SF7
GO:0007179 transforming growth factor beta receptor signaling pathway PR:O95405-1 hZFYVE9/iso:1

PMID:10615055
GO:0060390 regulation of SMAD protein signal transduction PR:O95405-1 hZFYVE9/iso:1

PMID:11877415, PMID:12356868
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005769 early endosome PR:O95405-1 hZFYVE9/iso:1

PMID:11877415, PMID:12356868, PMID:12432064
GO:0005615 extracellular space PR:O95405-2 hZFYVE9/iso:2

PMID:9582421
PR:O95405-3 hZFYVE9/iso:3

PMID:9582421

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