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Protein Ontology Report - hEGFR/SigPep-/Phos:4

PR:000049851 - http://purl.obolibrary.org/obo/PR_000049851
Ontology Information
PRO ID PR:000049851 Show OBO stanza / PAF
PRO name epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human)
Synonyms
PRO-short-label: hEGFR/SigPep-/Phos:4
PRO-proteoform-std: UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046
Definition An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified on an inhibitory site located in the kinase domain (sub-kinase domain III) corresponding to a phosphoserine at position 768 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046. [PMID:10347170, PRO:KER]
Comment Evidence=(ECO:0000006, based on PMID:10347170). Kinase=("CAMKII"; PR:000003197; Ser-768).
PRO Category organism-modification
Parent PR:000028422 epidermal growth factor receptor, signal peptide removed form (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000049851
hEGFR/SigPep-/Phos:4
Ser-768, MOD:00046
capable_of GO:0004713 protein tyrosine kinase activity decreased relative to PR:000049852 hEGFR/SigPep-/UnPhos:4 PMID:10347170

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