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Protein Ontology Report - mZC3HAV1/iso:3/IpCysEst:1

PR:000044350 - http://purl.obolibrary.org/obo/PR_000044350
Ontology Information
PRO ID PR:000044350 Show OBO stanza / PAF
PRO name zinc finger CCCH-type antiviral protein 1 isoform 3 prenylated-cysteine methyl ester 1 (mouse)
Synonyms
PRO-short-label: mZC3HAV1/iso:3/IpCysEst:1
PRO-proteoform-std: UniProtKB:D3Z5I1, 1-993, Cys-993, MOD:00116
Definition A zinc finger CCCH-type antiviral protein 1 isoform 3 (mouse) that has been farnesylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. UniProtKB:D3Z5I1, 1-993, Cys-993, MOD:01116. [PMID:23776219, PRO:HJD]
Comment Note: The processing at the C-terminus is inferred by curator based on the known farnesylation processing of CaaX bearing proteins (PMID:10548882).
PRO Category organism-modification
Parent PR:D3Z5I1 zinc finger CCCH-type antiviral protein 1 isoform 3 (mouse)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044350
mZC3HAV1/iso:3/IpCysEst:1
Cys-993, MOD:01116 		located_in GO:0005764 lysosome MGI:5499037, PMID:23776219
located_in GO:0005770 late endosome MGI:5499037, PMID:23776219
participates_in GO:0039507 suppression by virus of host molecular function MGI:5499037, PMID:23776219
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0039507 suppression by virus of host molecular function PR:000044350 mZC3HAV1/iso:3/IpCysEst:1
Cys-993, MOD:01116
MGI:5499037, PMID:23776219
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005770 late endosome PR:000044350 mZC3HAV1/iso:3/IpCysEst:1
Cys-993, MOD:01116
MGI:5499037, PMID:23776219
GO:0005764 lysosome PR:000044350 mZC3HAV1/iso:3/IpCysEst:1
Cys-993, MOD:01116
MGI:5499037, PMID:23776219

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