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Protein Ontology Report - hYAP1/iso:3/Phos:1

PR:000037508 - http://purl.obolibrary.org/obo/PR_000037508
Ontology Information
PRO ID PR:000037508 Show OBO stanza / PAF
PRO name transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human)
Synonyms
PRO-short-label: hYAP1/iso:3/Phos:1
PRO-proteoform-std: UniProtKB:P46937-3, Tyr-357, MOD:00048
Definition A transcriptional coactivator YAP1 isoform 3 (human) that has been phosphorylated on a Tyr residue at position 357. UniProtKB:P46937-3, Tyr-357, MOD:00048. [PMID:21214929, PMID:21945154, PRO:KER]
Comment Kinase=("ABL1"; PR:P00519; Tyr-357).
PRO Category organism-modification
Parent PR:P46937-3 transcriptional coactivator YAP1 isoform 3 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037508
hYAP1/iso:3/Phos:1
Tyr-357, MOD:00048 		associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:21562856
associated_with_disease_suppression DOID:162 cancer PMID:21214929
capable_of GO:0005515 protein binding increased relative to PR:000037507 hYAP1/iso:3/UnPhos:1 with PR:O15350 hTP73 PMID:21214929, PMID:21562856
located_in GO:0005634 nucleus PMID:21562856
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000037508 hYAP1/iso:3/Phos:1
Tyr-357, MOD:00048
PMID:21562856

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