| PRO ID |
PR:000036822
Show OBO stanza
|
| PRO name |
E protein |
| Synonyms |
| PRO-short-label: |
DenV-E |
| EXACT: |
Envelope protein E |
|
| Definition |
A dengue virus genome polyprotein proteolytic cleavage product that is a structural protein containing two alpha-helices (EH1 and EH2) at the C-terminus and two transmembrane domains (ET1 and ET2) of the dengue virus RNA genome. It contains two N-linked glycosylation sites, at Asn-67 and Asn-153. Example: UniProtKB:P29990, 281-775, Asn-347/Asn-433, MOD:00160.
[PMID:17459925, PMID:23300717, PRO:DAN, PRO:ES]
|
| Comment |
Requested by=IDODEN. The E protein is responsible for eliciting the majority of the protective dengue virus antibody response. It covers the virion surface arranged in anti-parallel dimers containing three structural and antigenic domains [PMID:22709350, PRO:ES]. |
| PRO Category |
modification |
| Parent |
PR:000036818 dengue virus genome polyprotein proteolytic cleavage product |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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