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Protein Ontology Report - hCUL1/iso:1/Nedd:1

PR:000036454 - http://purl.obolibrary.org/obo/PR_000036454
Ontology Information
PRO ID PR:000036454 Show OBO stanza / PAF
PRO name cullin-1 isoform 1 neddylated 1 (human)
Synonyms
PRO-short-label: hCUL1/iso:1/Nedd:1
PRO-proteoform-std: UniProtKB:Q13616-1, Lys-720, MOD:01150
Definition A fungal/metazoan cullin-1 isoform 1 neddylated 1 in human. UniProtKB:Q13616-1, Lys-720, MOD:01150. [PMID:10713156, PMID:10921923, PMID:17098746, PMID:8681378, PRO:CNA]
PRO Category organism-modification
Parent PR:000000542 fungal/metazoan cullin-1 isoform 1 neddylated 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036454
hCUL1/iso:1/Nedd:1
Lys-720, MOD:01150 		part_of GO:0019005 SCF ubiquitin ligase complex PMID:10713156, PMID:10921923, PMID:17098746
participates_in GO:0008285 negative regulation of cell population proliferation PMID:8681378
participates_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PMID:10713156, PMID:10921923
participates_in GO:0051726 regulation of cell cycle PMID:8681378
participates_in GO:0097193 intrinsic apoptotic signaling pathway PMID:8681378
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0051726 regulation of cell cycle PR:000036454 hCUL1/iso:1/Nedd:1
Lys-720, MOD:01150
PMID:8681378
GO:0008285 negative regulation of cell population proliferation PR:000036454 hCUL1/iso:1/Nedd:1
Lys-720, MOD:01150
PMID:8681378
GO:0097193 intrinsic apoptotic signaling pathway PR:000036454 hCUL1/iso:1/Nedd:1
Lys-720, MOD:01150
PMID:8681378
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PR:000036454 hCUL1/iso:1/Nedd:1
Lys-720, MOD:01150
PMID:10713156, PMID:10921923

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