Entry Report [PIR] - PR:000035423

Protein Ontology Report - hATM/Phos:2

PR:000035423 - http://purl.obolibrary.org/obo/PR_000035423

Protein Forms Annotations

Ontology Information

PRO ID

PR:000035423 Show OBO stanza / PAF

PRO name

serine-protein kinase ATM phosphorylated 2 (human)

Synonyms

PRO-short-label:	hATM/Phos:2
PRO-proteoform-std:	UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046

Definition

A serine-protein kinase ATM phosphorylated 2 in human. This phosphorylated form is observed during mitosis and spindle depolymerization (nocodazole). Ser-1403 is phosphorylated by Aurora B kinase. UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046. [PMID:22099307, PRO:KER]

Comment

Kinase=("AURKB"; PR:Q96GD4).

PRO Category

organism-modification

Parent

PR:000035422 serine-protein kinase ATM phosphorylated 2

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	capable_of	GO:0004672 protein kinase activity increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307
	located_in	GO:0030496 midbody	PMID:22099307
	located_in	GO:0000779 condensed chromosome, centromeric region	PMID:22099307
	located_in	GO:0051233 spindle midzone	PMID:22099307
	located_in	GO:0000922 spindle pole	PMID:22099307
	located_in	GO:0005694 chromosome	PMID:22099307
	participates_in	GO:0031577 spindle checkpoint signaling increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0031577 spindle checkpoint signaling	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046 increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0000779 condensed chromosome, centromeric region	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0051233 spindle midzone	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0000922 spindle pole	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0030496 midbody	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0005694 chromosome	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307

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