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Protein Ontology Report - hSIAH1/iso:1/Phos:1

PR:000025641 - http://purl.obolibrary.org/obo/PR_000025641
Ontology Information
PRO ID PR:000025641 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 (human)
Synonyms
PRO-short-label: hSIAH1/iso:1/Phos:1
PRO-proteoform-std: UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048
Definition An E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 in human. UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048. [PMID:16230351, PMID:9482736, PRO:DAN, PRO:JAN]
PRO Category organism-modification
Parent PR:000025627 E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025641
hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048 		capable_of GO:0005515 protein binding increased relative to PR:000045369 hSIAH1/iso:1/UnPhos:1 with PR:Q69ZI1-1 mSH3RF1/iso:1 PMID:16230351
participates_in GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351
participates_in GO:0043525 positive regulation of neuron apoptotic process PMID:16230351
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351
GO:0043525 positive regulation of neuron apoptotic process PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351

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