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Protein Ontology Report - PIAS2

PR:000003436 - http://purl.obolibrary.org/obo/PR_000003436
Ontology Information
PRO ID PR:000003436 Show OBO stanza / PAF
PRO name E3 SUMO-protein ligase PIAS2
Synonyms
PRO-short-label: PIAS2
EXACT: ARIP3; Msx-interacting zinc finger protein; PIAS-NY protein; androgen receptor-interacting protein 3; miz1; protein inhibitor of activated STAT x; protein inhibitor of activated STAT2
Gene-based: PIASX
RELATED: DAB2-interacting protein; DIP
Definition An E3 SUMO-protein ligase PIAS that is a translation product of the human PIAS2 gene or a 1:1 ortholog thereof. [MGI:1096566, PRO:HJD]
PRO Category gene
Parent PR:000003444 E3 SUMO-protein ligase PIAS
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 2 organism-sequence 8
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q8C5D8-2
mPIAS2/iso:2
capable_of GO:0005515 protein binding with PR:P98078-3 mDAB2/iso:3 MGI:1929027, PMID:11104669
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:1929027, PMID:11104669
PR:Q8C5D8-1
mPIAS2/iso:1
capable_of GO:0003677 DNA binding MGI:894957, PMID:9256341
capable_of GO:0005515 protein binding with PR:P08152-2 mEGR2/iso:Short MGI:3629292, PMID:16675951
capable_of GO:0005515 protein binding with PR:P29037 mTBP PMID:16522640
capable_of GO:0019789 SUMO transferase activity PMID:15767674
located_in GO:0016604 nuclear body MGI:3629292, PMID:16675951
located_in GO:0005634 nucleus PMID:16522640
participates_in GO:0016925 protein sumoylation PMID:15767674
participates_in GO:0045893 positive regulation of transcription, DNA-templated MGI:3723333, PMID:17623776
participates_in GO:0006357 regulation of transcription by RNA polymerase II MGI:894957, PMID:9256341
participates_in GO:0045667 regulation of osteoblast differentiation MGI:3723333, PMID:17623776
participates_in GO:0006351 transcription, DNA-templated MGI:894957, PMID:9256341
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0016925 protein sumoylation PR:Q8C5D8-1 mPIAS2/iso:1

PMID:15767674
GO:0045667 regulation of osteoblast differentiation PR:Q8C5D8-1 mPIAS2/iso:1

MGI:3723333, PMID:17623776
GO:0006351 transcription, DNA-templated PR:Q8C5D8-1 mPIAS2/iso:1

MGI:894957, PMID:9256341
GO:0045893 positive regulation of transcription, DNA-templated PR:Q8C5D8-1 mPIAS2/iso:1

MGI:3723333, PMID:17623776
GO:0006357 regulation of transcription by RNA polymerase II PR:Q8C5D8-1 mPIAS2/iso:1

MGI:894957, PMID:9256341
GO:0045944 positive regulation of transcription by RNA polymerase II PR:Q8C5D8-2 mPIAS2/iso:2

MGI:1929027, PMID:11104669
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0016604 nuclear body PR:Q8C5D8-1 mPIAS2/iso:1

MGI:3629292, PMID:16675951
GO:0005634 nucleus PR:Q8C5D8-1 mPIAS2/iso:1

PMID:16522640

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