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Protein Ontology Report - NRP1

PR:000001900 - http://purl.obolibrary.org/obo/PR_000001900
Ontology Information
PRO ID PR:000001900 Show OBO stanza / PAF
PRO name neuropilin-1
Synonyms
PRO-short-label: NRP1
EXACT: A5 protein; BDCA-4; CD304; blood dendritic cell antigen 4; vascular endothelial cell growth factor 165 receptor
Gene-based: NRP; VEGF165R
RELATED: BDCA4
Definition A protein that is a translation product of the human NRP1 gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 5
sequence 2 organism-sequence 4
modification 5 organism-modification 8
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036632
hNRP1/iso:1/ClvOGlyco:2
Ser-612, MOD:00213 		capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding decreased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P35968 hKDR PMID:16763549
capable_of GO:0005515 protein binding increased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549
has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549
participates_in GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549
PR:000001900
NRP1
has_part Pfam:PF00754 F5/8 type C domain
has_part Pfam:PF00431 CUB domain
has_part Pfam:PF00629 MAM domain, meprin/A5/mu
PR:000036635
hNRP1/iso:1/SigPep-
capable_of GO:0005515 protein binding with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549
capable_of GO:0005515 protein binding with PR:P49763-3 hPGF/iso:PlGF-2 PMID:11986311
capable_of GO:0005515 protein binding with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:11986311
capable_of GO:0008201 heparin binding PMID:11986311
capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35968 hKDR PMID:16763549
has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549
PR:P97333
mNRP1
capable_of GO:0005515 protein binding with PR:P49766-2 mVEGFB/iso:VEGF-B167 PMID:10409677
capable_of GO:0005515 protein binding with PR:000036636 mVEGFB/iso:1/Clv:1 PMID:10409677
PR:000036631
hNRP1/iso:1/ClvOGlyco:1
Ser-612, MOD:00215 		capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35968 hKDR PMID:16763549
capable_of GO:0005515 protein binding increased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549
has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549
participates_in GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PR:000036631 hNRP1/iso:1/ClvOGlyco:1
Ser-612, MOD:00215
PMID:16763549
PR:000036632 hNRP1/iso:1/ClvOGlyco:2
Ser-612, MOD:00213
PMID:16763549

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