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Protein Ontology Report - IL24

PR:000001474 - http://purl.obolibrary.org/obo/PR_000001474
Ontology Information
PRO ID PR:000001474 Show OBO stanza / PAF
PRO name interleukin-24
Synonyms
PRO-short-label: IL24
EXACT: IL-24; IL-4-induced secreted protein; MDA-7; Th2-specific cytokine FISP; melanoma differentiation-associated gene 7 protein; suppression of tumorigenicity 16 protein
Gene-based: MDA7; ST16
Definition A class 2 cytokine, IL-10 type that is a translation product of the human IL24 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000001335 class 2 cytokine, IL-10 type
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 2 organism-sequence 6
modification 1 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035509
IL24/iso:2
participates_in GO:0043066 negative regulation of apoptotic process MGI:3821693, PMID:18708357
participates_in GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MGI:3821693, PMID:18708357
PR:A3QQZ3
mIL24/iso:2
located_in GO:0005783 endoplasmic reticulum MGI:3821693, PMID:18708357
participates_in GO:0043066 negative regulation of apoptotic process MGI:3821693, PMID:18708357
participates_in GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MGI:3821693, PMID:18708357
PR:Q925S4-1
mIL24/iso:1
capable_of GO:0005515 protein binding with PR:A3QQZ3 mIL24/iso:2 MGI:3821693, PMID:18708357
located_in GO:0005576 extracellular region MGI:3821693, PMID:18708357
participates_in GO:0008285 negative regulation of cell population proliferation MGI:3821693, PMID:18708357
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0043066 negative regulation of apoptotic process PR:000035509 IL24/iso:2

MGI:3821693, PMID:18708357
PR:A3QQZ3 mIL24/iso:2

MGI:3821693, PMID:18708357
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PR:000035509 IL24/iso:2

MGI:3821693, PMID:18708357
PR:A3QQZ3 mIL24/iso:2

MGI:3821693, PMID:18708357
GO:0008285 negative regulation of cell population proliferation PR:Q925S4-1 mIL24/iso:1

MGI:3821693, PMID:18708357
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005576 extracellular region PR:Q925S4-1 mIL24/iso:1

MGI:3821693, PMID:18708357
GO:0005783 endoplasmic reticulum PR:A3QQZ3 mIL24/iso:2

MGI:3821693, PMID:18708357

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