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Protein Ontology Report - IL6R

PR:000001394 - http://purl.obolibrary.org/obo/PR_000001394
Ontology Information
PRO ID PR:000001394 Show OBO stanza / PAF
PRO name interleukin-6 receptor subunit alpha
Synonyms
PRO-short-label: IL6R
EXACT: CD126; IL-6 receptor subunit alpha; IL-6R 1; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; gp80; membrane glycoprotein 80
Gene-based: Il6ra
Definition A protein that is a translation product of the human IL6R gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 3 organism-sequence 3
modification 5 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P22272-1
mIL6R/iso:1
capable_of GO:0004915 interleukin-6 receptor activity PMID:1312474
capable_of GO:0019981 interleukin-6 binding PMID:1312474
located_in GO:0009986 cell surface PMID:1312474
participates_in GO:0070102 interleukin-6-mediated signaling pathway PMID:1312474
PR:000044514
mIL6R/iso:1/Clv:soluble
capable_of GO:0004915 interleukin-6 receptor activity PMID:8477802
capable_of GO:0019981 interleukin-6 binding PMID:8477802
located_in GO:0005615 extracellular space PMID:8477802
participates_in GO:0070102 interleukin-6-mediated signaling pathway PMID:8477802
PR:000001394
IL6R
has_part Pfam:PF00047 Immunoglobulin domain
has_part Pfam:PF09240 Interleukin-6 receptor alpha chain, binding
has_part Pfam:PF00041 Fibronectin type III domain
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0070102 interleukin-6-mediated signaling pathway PR:000044514 mIL6R/iso:1/Clv:soluble

PMID:8477802
PR:P22272-1 mIL6R/iso:1

PMID:1312474
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:P22272-1 mIL6R/iso:1

PMID:1312474
GO:0005615 extracellular space PR:000044514 mIL6R/iso:1/Clv:soluble

PMID:8477802

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