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Protein Ontology Report - hKCNQ1/var:A300T

PR:000000874 - http://purl.obolibrary.org/obo/PR_000000874
Ontology Information
PRO ID PR:000000874 Show OBO stanza / PAF
PRO name voltage-gated potassium channel subunit KCNQ1 sequence variant A300T (human)
Synonyms
PRO-short-label: hKCNQ1/var:A300T
EXACT: voltage-gated potassium channel subunit KCNQ1 sequence variant 61 (human)
PRO-proteoform-std: UniProtKB:P51787-1, Ala-300, CHEBI:30013
Definition A potassium voltage-gated channel subfamily KQT member 1 (human) that has a Thr residue at the position equivalent to Ala-300 of the amino acid sequence represented by UniProtKB:P51787-1. Example: UniProtKB:P51787-1, Ala-300, CHEBI:30013. [PMID:9641694, PRO:CNA, PRO:DAN]
Comment Note: This residue is located in the pore region between segments S5 and S6.
PRO Category organism-sequence
Parent PR:P51787 potassium voltage-gated channel subfamily KQT member 1 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000874
hKCNQ1/var:A300T
Ala-300, CHEBI:30013
associated_with_disease_progression DOID:2843 long QT syndrome PMID:9641694
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:9641694

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