| PRO ID |
PR:000000659
Show OBO stanza
|
| PRO name |
smad3 isoform 1 phosphorylated 2 |
| Synonyms |
| PRO-short-label: |
SMAD3/iso:1/Phos:2 |
|
| Definition |
A smad3 isoform 1 phosphorylated form in which the phosphorylation occurs at the N-terminal Px[ST]P motif and the clusters of [ST]P motifs within the MH1-MH2 domain linker region by G1 cyclin-dependent kinases (CDK4 and CDK2) leading to CDK inhibition of its transcriptional activity and antiproliferative function. Example: UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046.
[PMID:15241418, PRO:CNA, PRO:DAN]
|
| PRO Category |
modification |
| Parent |
PR:000000578 smad3 isoform 1 phosphorylated form |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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