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Protein Ontology Report - ROCK1

PR:000000120 - http://purl.obolibrary.org/obo/PR_000000120
Ontology Information
PRO ID PR:000000120 Show OBO stanza / PAF
PRO name Rho-associated protein kinase 1
Synonyms
PRO-short-label: ROCK1
EXACT: ROCK-I; Rho-associated, coiled-coil-containing protein kinase I; p160 ROCK-1; p160ROCK; renal carcinoma antigen NY-REN-35; rho-associated, coiled-coil-containing protein kinase 1
Definition A Rho-associated protein kinase that is a translation product of the human ROCK1 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000024 Rho-associated protein kinase
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 5
modification 5 organism-modification 3
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036476
mROCK1/iso:1/Clv:1
participates_in GO:0010659 cardiac muscle cell apoptotic process PMID:16983089
participates_in GO:0030036 actin cytoskeleton organization PMID:11283607, PMID:16983089
PR:000044586
hROCK1/iso:1/UnMod
capable_of GO:0004674 protein serine/threonine kinase activity PMID:11283607
capable_of GO:0004674 protein serine/threonine kinase activity PMID:15699075
PR:Q13464-1
hROCK1/iso:1
capable_of GO:0031267 small GTPase binding PMID:14660612, PMID:15475352
capable_of GO:0004674 protein serine/threonine kinase activity PMID:8798490
participates_in GO:0006468 protein phosphorylation PMID:10436159
participates_in GO:0030036 actin cytoskeleton organization PMID:10436159
participates_in GO:0007266 Rho protein signal transduction PMID:8798490
participates_in GO:0051260 protein homooligomerization PMID:15291762
PR:000026340
hROCK1/iso:1/Clv:1
capable_of GO:0004674 protein serine/threonine kinase activity increased relative to PR:000002529 ROCK1/iso:1/UnMod PMID:11283607
participates_in GO:0006468 protein phosphorylation PMID:11283607
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006468 protein phosphorylation PR:000026340 hROCK1/iso:1/Clv:1

PMID:11283607
PR:Q13464-1 hROCK1/iso:1

PMID:10436159
GO:0007266 Rho protein signal transduction PR:Q13464-1 hROCK1/iso:1

PMID:8798490
GO:0010659 cardiac muscle cell apoptotic process PR:000036476 mROCK1/iso:1/Clv:1

PMID:16983089
GO:0030036 actin cytoskeleton organization PR:000036476 mROCK1/iso:1/Clv:1

PMID:11283607, PMID:16983089
PR:Q13464-1 hROCK1/iso:1

PMID:10436159
GO:0051260 protein homooligomerization PR:Q13464-1 hROCK1/iso:1

PMID:15291762

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