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Protein Ontology Report - hTGFBR2/var:N435S

PR:000000062 - http://purl.obolibrary.org/obo/PR_000000062
Ontology Information
PRO ID PR:000000062 Show OBO stanza / PAF
PRO name TGF-beta receptor type-2 sequence variant N435S (human)
Synonyms
PRO-short-label: hTGFBR2/var:N435S
EXACT: TGF-beta receptor type-2 sequence variant 6 (human)
PRO-proteoform-std: UniProtKB:P37173-1, Asn-435, CHEBI:29999
Definition A TGF-beta receptor type-2 (human) that has a Ser residue at the position equivalent to Asn-435 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Asn-435, CHEBI:29999. [PMID:11212236, PRO:CNA, PRO:DAN]
PRO Category organism-sequence
Parent PR:P37173 TGF-beta receptor type-2 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000062
hTGFBR2/var:N435S
Asn-435, CHEBI:29999 		capable_of GO:0005026 transforming growth factor beta receptor activity, type II decreased relative to PR:000000409 TGFBR2/iso:RII-1/SigPep- PMID:11212236
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000000062 hTGFBR2/var:N435S
Asn-435, CHEBI:29999
PMID:11212236

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