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Protein Ontology Report - hTGFBR2/var:A355P

PR:000000060 - http://purl.obolibrary.org/obo/PR_000000060
Ontology Information
PRO ID PR:000000060 Show OBO stanza / PAF
PRO name TGF-beta receptor type-2 sequence variant A355P (human)
Synonyms
PRO-short-label: hTGFBR2/var:A355P
EXACT: TGF-beta receptor type-2 sequence variant 4 (human)
PRO-proteoform-std: UniProtKB:P37173-1, Ala-355, CHEBI:50342
Definition A TGF-beta receptor type-2 (human) that has a Pro residue at the position equivalent to Ala-355 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Ala-355, CHEBI:50342. [PMID:15731757, PRO:CNA, PRO:DAN]
PRO Category organism-sequence
Parent PR:P37173 TGF-beta receptor type-2 (human)
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000060
hTGFBR2/var:A355P
Ala-355, CHEBI:50342 		associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757
located_in GO:0016021 integral component of membrane PMID:15731757
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15731757
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000000060 hTGFBR2/var:A355P
Ala-355, CHEBI:50342
PMID:15731757
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0016021 integral component of membrane PR:000000060 hTGFBR2/var:A355P
Ala-355, CHEBI:50342
PMID:15731757

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