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Protein Ontology Report - thrombospondin subgroup A

PR:000000029 - http://purl.obolibrary.org/obo/PR_000000029
Ontology Information
PRO ID PR:000000029 Show OBO stanza / PAF
PRO name thrombospondin subgroup A
Definition A protein with a core domain composition consisting of a procollagen homology domain and three TSR domains at the N terminus followed by three or four EGF-type repeats, a series of seven contiguous calcium-binding repeats (the thrombospondin type 3 repeats), and a globular carboxyl-terminal domain. [PMID:10842357]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000029
thrombospondin subgroup A
capable_of GO:0008201 heparin binding PIRSF:PIRSF002478
capable_of GO:0004866 endopeptidase inhibitor activity PIRSF:PIRSF002478
has_part Pfam:PF05735 Thrombospondin C-terminal region PIRSF:PIRSF002478
has_part Pfam:PF00093 von Willebrand factor type C domain PIRSF:PIRSF002478
has_part Pfam:PF02412 Thrombospondin type 3 repeat PIRSF:PIRSF002478
has_part Pfam:PF00008 EGF-like domain PIRSF:PIRSF002478
participates_in GO:0016525 negative regulation of angiogenesis PIRSF:PIRSF002478
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0016525 negative regulation of angiogenesis PR:000000029 thrombospondin subgroup A

PIRSF:PIRSF002478

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