back to PRO homepage

Protein Ontology Report - smad protein

PR:000000027 - http://purl.obolibrary.org/obo/PR_000000027
Ontology Information
PRO ID PR:000000027 Show OBO stanza / PAF
PRO name smad protein
Definition A protein with core domain composition consisting of one MH1 domain (Pfam:PF03165) at the N terminus and one MH2 domain (Pfam:PF03166) at the C-terminus, separated by a non-conserved linker region. Smad proteins are mediators of signal transduction in transforming growth factor beta (TGF-beta) superfamily pathways. [PRO:CNA]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000027
smad protein
capable_of GO:0005515 protein binding PIRSF:PIRSF037286
has_part Pfam:PF03166 MH2 domain PIRSF:PIRSF037286
has_part Pfam:PF03165 MH1 domain PIRSF:PIRSF037286
participates_in GO:0006355 regulation of transcription, DNA-templated PIRSF:PIRSF037286
participates_in GO:0007165 signal transduction PIRSF:PIRSF037286
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006355 regulation of transcription, DNA-templated PR:000000027 smad protein

PIRSF:PIRSF037286
GO:0007165 signal transduction PR:000000027 smad protein

PIRSF:PIRSF037286

top