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Protein Ontology Report - HLH DNA-binding protein inhibitor

PR:000000003 - http://purl.obolibrary.org/obo/PR_000000003
Ontology Information
PRO ID PR:000000003 Show OBO stanza / PAF
PRO name HLH DNA-binding protein inhibitor
Synonyms
BROAD: bHLH clade D; bHLH class V
EXACT: DNA-binding protein inhibitor ID
RELATED: ID protein
Definition A protein that belongs to the clade D of the bHLH proteins (see PMID:20219281) with a core domain composition consisting of a helix-loop-helix DNA-binding domain (Pfam:PF00010) (HLH), common to the basic HLH family of transcription factors, but lacking the DNA binding domain to the consensus E box response element (CANNTG). By binding to basic HLH transcription factors, proteins in this class regulate gene expression. [PMID:20219281, PRO:CNA]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000003
HLH DNA-binding protein inhibitor
capable_of GO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF005808
has_part Pfam:PF00010 Helix-loop-helix DNA-binding domain PIRSF:PIRSF005808
participates_in GO:0006355 regulation of transcription, DNA-templated PIRSF:PIRSF005808
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006355 regulation of transcription, DNA-templated PR:000000003 HLH DNA-binding protein inhibitor

PIRSF:PIRSF005808

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