PMID: 22977173 RLIMS-P 77 Check other iTextMine results Issue Report
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Legend: SUBSTRATE KINASE INTERACTANT SITE GENE MIRNA ANOMALY EXPRESSION DISEASE OUTCOME/RESPONSE SR_DRUG DRUG CELL TRIGGER Normalized
Tool: RLIMS-P
| PTM enzyme | Substrate | Site | Sentence |
|---|---|---|---|
| RPA32 (P15927) | Ser-8, Ser-4 | 22.4, 29.1, 29.3 (results) 57.2 (discussion) | |
| RPA32 (P15927) | Ser-12 | 31.1, 31.2, 31.3, 31.4, 39.1, 40.3, 40.6 (results) 57.2, 57.4 (discussion) | |
| RPA | 0.1 (abstract) 54.5, 56.1, 57.1 (discussion) | ||
| RPA32 (P15927) | Thr-21, Ser-8, Ser-33, Ser-4 | 57.2, 57.4 (discussion) | |
| DNA-PKcs (P78527) | RPA | 54.6 (discussion) | |
| ATR (Q13535) | RPA32 (P15927) | Ser-33 | 5.2, 5.3 (introduction) 25.1, 30.1, 30.6 (results) 54.8 (discussion) |
| DNA-PKcs (P78527) | RPA32 (P15927) | 5.12 (introduction) 54.9 (discussion) | |
| RPA32 (P15927) | 5.1, 5.5, 5.10 (introduction) 23.6, 26.1, 27.1, 33.3, 33.4, 34.2, 46.1 (results) 51.1, 52.1, 54.4, 56.4, 58.3 (discussion) | ||
| DNA-PKcs (P78527) | Thr-21, Ser-4, Ser-8 | 56.4 (discussion) | |
| ATR (Q13535) | Ser-33 | 56.4 (discussion) | |
| RPA | Ser-33, Thr-21, Ser-12 | 56.2 (discussion) | |
| RPA | Thr-21, Ser-33, Ser-4, Ser-8, Ser-12 | 56.2 (discussion) | |
| PIKK | RPA32 (P15927) | 21.1 (results) 58.6, 59.1 (discussion) | |
| complex RPA32 | 59.3 (discussion) | ||
| RPA32 (P15927) | MRE11, TopBP1 | 59.3 (discussion) | |
| PIKKs/CDK | RPA32 (P15927) | 60.1 (discussion) | |
| DNA-PKcs (P78527) | RPA32 (P15927) | Ser-4, Ser-8 | 52.2, 52.4 (discussion) |
| RPA32 (P15927) | Ser-33 | 25.1, 25.3, 25.4, 30.1, 30.3, 30.4, 30.5 (results) 52.2, 52.3 (discussion) | |
| ATM (Q13315) | RPA32 (P15927) | Ser-8, Ser-4 | 52.2, 52.5 (discussion) |
| RPA32 (P15927) | Thr-21, Ser-29 | 52.2 (discussion) | |
| DNA-PKcs (P78527) | RPA32 (P15927) | Ser-8, Ser-4 | 5.11 (introduction) 38.1, 42.1 (results) 52.2, 52.5 (discussion) |
| DNA-PK (P78527) | ATM (Q13315) | Thr-21 | 53.1 (discussion) |
| DNA-PKcs (P78527) | Thr-21 | 53.2 (discussion) | |
| ATR (Q13535) | H2AX (P16104) | Ser-33 | 53.6, 53.7 (discussion) |
| ATM (Q13315), DNA-PKcs (P78527) | H2AX (P16104) | 53.6 (discussion) | |
| ATR (Q13535) | H2AX (P16104) | Thr-21, Ser-8, Ser-4 | 53.6, 53.7 (discussion) |
| RPA32 (P15927) | Thr-21 | 24.1, 27.4 (results) | |
| Chk1 (O14757) | Ser-4, Ser-8 | 36.1 (results) | |
| Chk1 (O14757) | RPA (22) | 4.7 (introduction) | |
| ATR (Q13535), DNA-PKcs (P78527) | RPA | 4.6 (introduction) | |
| DNA-PKcs (P78527), ATM (Q13315) | RPA32 (P15927) | 4.6 (introduction) | |
| PIKK | 28.1 (results) | ||
| In vitro | RPA32 (P15927) | 28.2 (results) | |
| ATR (Q13535) | RPA32 (P15927) | Ser-29, Ser-8, Ser-4 | 25.1 (results) |
| RPA32 (P15927) | Ser-8, Ser-33 | 25.1, 25.4 (results) | |
| S4A/S8A mutant | Ser-33 | 25.2 (results) | |
| MRE11 | 34.3, 34.5, 34.6, 35.5 (results) | ||
| Chk2 | 34.2 (results) | ||
| TopBP1 | 34.3, 34.8, 35.7, 35.8 (results) | ||
| KAP1 | 34.2 (results) | ||
| RPA32 (P15927) | Ser-4, Ser-8 | 27.4, 27.5, 34.1, 45.1, 48.1 (results) | |
| DNA-PK (P78527) | RPA32 (P15927) | Ser-33 | 27.4, 27.7 (results) |
| DNA-PK (29) (P78527) | RPA32 (P15927) | Ser-29, Thr-21, Ser-23, Ser-4 | 27.2 (results) |
| DNA-PK (P78527) | RPA32 (P15927) | Thr-21, Ser-4, Ser-8 | 27.4, 27.7 (results) |
| DNA-PK (Figure 2A–C) (P78527) | RPA32 (P15927) | Thr-21, Ser-4, Ser-8 | 27.4 (results) |
| RPA32 (P15927) | Ser-23, Ser-29 | 27.8 (results) | |
| TopBP1, MRE11 | Ser-8, Ser-4 | 32.1 (results) | |
| CDK2/cyclin A | RPA32 (P15927) | Ser-23, Ser-29 | 5.2 (introduction) |
| RPA | Ser-8, Ser-33, Ser-29, Thr-21, Ser-4 | 5.6, 5.8 (introduction) | |
| RPA | Ser-8, Ser-4 | 5.8 (introduction) | |
| ATR (Q13535) | RPA32 (P15927) | Ser-29, Ser-23 | 5.2, 5.3 (introduction) |
| RPA | Ser-4, Ser-8 | 5.8, 5.9 (introduction) | |
| RPA32 (P15927) | Thr-21, Ser-8, Ser-4, Ser-33 | 23.1, 23.3 (results) | |
| DNA-PK (P78527) | RPA32 (P15927) | Ser-8, Ser-4 | 29.1, 29.4 (results) |
| RPA32 (P15927) | Ser-33, Ser-8, Ser-4, Ser-12 | 29.1 (results) | |
| DNA-PK (P78527) | RPA32 (P15927) | Ser-8 | 29.1, 29.4 (results) |
| WT | Ser-12, Ser-13, Ser-8, Ser-4, Ser-33, Ser-11, Thr-21 | 22.1, 22.4 (results) | |
| RPA32 (P15927) | WT | Ser-8, Ser-4 | 22.4 (results) |
| RPA32 (P15927) | Ser-12, Ser-13, Ser-8, Ser-4, Ser-33, Ser-11, Thr-21 | 22.1, 22.4 (results) | |
| Chk1 (O14757) | Ser-317 | 38.2, 38.4 (results) | |
| Chk1 Ser345 | Ser-345 | 38.7 (results) | |
| Chk1 (O14757) | 37.3, 38.7 (results) | ||
| ATR (Q13535) | 33.2 (results) | ||
| ATM (Q13315) | Rad17 | 33.5 (results) | |
| ATM (Q13315) | Chk2 checkpoint proteins | 33.5 (results) | |
| ATM (Q13315) | KAP1 | 33.5 (results) | |
| Chk1 (O14757) | Ser-8, Ser-4 | 37.2 (results) | |
| ATR (Q13535) | Chk1 (O14757) | 37.1 (results) | |
| DNA-PKcs (P78527) | Ser-4, Ser-8 | 37.4 (results) | |
| DNA-PK (P78527) | RPA32 (P15927) | Ser-12 | 31.1 (results) |
| RPA32 (P15927) | Ser-10 | 47.3 (results) | |
| ATR (Q13535) | RPA32 (P15927) | 35.3 (results) | |
| ATR (Q13535) | RPA32 (P15927) | Thr-21, Ser-33 | 35.4 (results) |
| TopBP1’s ATR | 35.6 (results) | ||
| RPA32 (P15927) | Ser-4 | 43.9 (results) | |
| PIKK | RPA switches RPA | 58.1 (discussion) | |
| RPA32 (P15927) | Ser-12, Ser-4, Ser-33, Thr-21, Ser-8 | 40.3 (results) |