PMID: 9228045    RLIMS-P  2    Check other iTextMine results Issue Report


Title
1.Serine phosphorylation within a concise amino-terminal domain in nuclear respiratory factor 1 enhances DNA binding.
Abstract
4.Here, we establish that NRF-1 is a phosphoprotein in vivo.
5.Phosphorylation occurs on serine residues within a concise NH2-terminal domain with the major sites of phosphate incorporation at serines 39, 44, 46, 47, and 52.
6.The in vivo phosphorylation pattern can be approximated in vitro by phosphorylating recombinant NRF-1 with purified casein kinase II.
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Legend:   SUBSTRATE  KINASE  INTERACTANT  SITE  GENE  MIRNA  ANOMALY  EXPRESSION  DISEASE  OUTCOME/RESPONSE  SR_DRUG  DRUG  CELL  TRIGGER  Normalized

Tool: RLIMS-P

PTM enzymeSubstrateSiteSentence
NRF-1 (Q16656)4, 6
NRF-1 (Q16656)Ser4, 5