PMID: 26269590    RLIMS-P  2    Check other iTextMine results Issue Report


Title
1.The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function.
Abstract
3.The effect(s) of the cAMP pathway and kinase mediated phosphorylation of PC2 seem to be relevant to PC2 trafficking and its interaction with polycystin-1.
4.However, the role of PC2 phosphorylation in channel function is still poorly defined.
10.PKA directly phosphorylated PC2, which increased the mean open time but not the single channel conductance of the channel.
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Tool: RLIMS-P

PTM enzymeSubstrateSiteSentence
PC2 (Q13563)3, 4
PKAPC2 (Q13563)10