PMID: 27213455    RLIMS-P  28 eFIP  2 miRTex  5  Issue Report


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Legend:   SUBSTRATE  KINASE  INTERACTANT  SITE  GENE  MIRNA  ANOMALY  EXPRESSION  DISEASE  OUTCOME/RESPONSE  SR_DRUG  DRUG  CELL  TRIGGER  Normalized

Tool: RLIMS-P

PTM enzymeSubstrateSiteSentence
heterochromatin protein 1α

9.4 (other)

Rabin8

9.6, 17.4 (other)

MOB1 (Q9H8S9)Thr-35, Thr-12

29.4 (other)

TrcYki

21.8 (other)

HippoTrc

25.2 (other)

HippoWarts

25.2 (other)

MST1/2 (P26927, Q13188)LATS1/2 (O95835, Q9NRM7)

25.4 (other)

YAP (P46937)

23.7, 23.10, 26.5 (other)

YAP (P46937)Ser-127

23.5, 23.6, 26.6, 26.7 (other)

TAZ (Q16635)

23.10 (other)

YAP (P46937)Ser-397, Ser-366, Ser-381

23.3 (other)

NDR1/2 (Q15208, Q9Y2H1)

11.1, 33.1 (other)

LATS1/2 (O95835, Q9NRM7)

2.6 (introduction)

33.1, 37.5 (other)

LATS1/2 (O95835, Q9NRM7)YAP (P46937)Ser-109, Ser-127, Ser-61, Ser-164

22.4 (other)

Ndr1Ser-127

22.6 (other)

NDR1/2 (Q15208, Q9Y2H1)YAP (P46937)Ser-109, Ser-61, Ser-127, Ser-164

22.4 (other)

Ndr2Ser-127

22.6 (other)

LATS1/2 (O95835, Q9NRM7)YAP (P46937)Ser-127

22.5 (other)

NDR1/2 (Q15208, Q9Y2H1)YAP (P46937)Ser-127

22.5 (other)

T-loopT-loop

35.6 (conclusion)

LATS1/2 (O95835, Q9NRM7)YAP/TAZSer

2.3 (introduction)

MST1, MST3, MST2NDR1/2 (Q15208, Q9Y2H1)Thr-442, Thr-444

6.2 (other)

NDR1/2 (Q15208, Q9Y2H1)NDR1/2 (Q15208, Q9Y2H1)Ser-282, Ser-281

6.2 (other)

LATS1/2 (O95835, Q9NRM7)YAP/TAZ

37.3 (other)

CDC25A phosphataseSer-76

13.6 (other)

CDC25ASer-76

13.7 (other)

polarity protein Par3 (Partitioning defective 3) NDR1/2

17.5 (other)

AAK1

17.4 (other)

Tool: eFIP

PTM enzymeSubstrateSiteImpactInteractantSentence
MOB1 (Q9H8S9)Thr-12, Thr-35requiredNDR (Q15208)

29.4 (other)

T-loopT-loopa MOB co-activat

35.6 (conclusion)

Tool: miRTex

miRNAGeneRelation TypeDirectSentence
microRNA-135bNDR2MIRNA→TARGETyes

23.8 (other)

microRNA-135bTAZ (Q16635)MIRNA→TARGETyes

23.8 (other)

microRNA-135bNDR1/2 (Q15208, Q9Y2H1)MIRNA→TARGETyes

23.8 (other)

microRNA-135bMOB1BMIRNA→TARGETyes

23.8 (other)

microRNA-135bLATS2MIRNA→TARGETyes

23.8 (other)