PMID: 21533119 RLIMS-P 12 eFIP 9 miRTex 0 Issue Report
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Legend: SUBSTRATE KINASE INTERACTANT SITE GENE MIRNA ANOMALY EXPRESSION DISEASE OUTCOME/RESPONSE SR_DRUG DRUG CELL TRIGGER Normalized
Tool: RLIMS-P
| PTM enzyme | Substrate | Site | Sentence |
|---|---|---|---|
| Akt (P31749) | Ser-473 | 9.6 (methods) | |
| VEGFR2 (P35968) | Tyr-1175 | 9.7 (methods) 43.2, 43.3, 43.5, 48.1 (results) 56.5, 59.4 (discussion) | |
| VEGFR2 (P35968) | 0.6 (abstract) 42.1, 44.11, 45.1, 47.1, 48.2, 48.6, 48.7, 50.1, 50.3 (results) 56.6, 57.2, 59.3, 62.1 (discussion) | ||
| leptin (P41159) | nitric oxide synthase (eNOS) | 61.3 (discussion) | |
| leptin causes rapid VEGFR-2 | 53.4 (discussion) | ||
| VEGFR2 (P35968), Stat-3 | 57.2 (discussion) | ||
| epidermal growth factor (EGF) receptor | 57.3 (discussion) | ||
| Akt (P31749) | 0.6 (abstract) 36.2, 36.3, 44.9, 46.4 (results) 54.6, 54.8 (discussion) | ||
| GSK3β | 44.9, 46.4 (results) | ||
| Stat-3 | 44.11, 48.3, 48.4 (results) | ||
| p38MAPK | 0.6 (abstract) 35.2, 46.4 (results) | ||
| vascular endothelial growth factor receptor 2 (VEGFR2) (P35968) | Tyr-1175 | 0.5 (abstract) 4.3 (introduction) |
Tool: eFIP
| PTM enzyme | Substrate | Site | Impact | Interactant | Sentence |
|---|---|---|---|---|---|
| VEGFR2 (P35968) | Tyr-1175 | detectable VEGF | 43.5 (results) | ||
| VEGFR2 (P35968) | Tyr-1175 | further | leptin (P41159) | 59.4 (discussion) | |
| VEGFR2 (P35968) | ObRb results | 62.1 (discussion) | |||
| Akt (P31749) | p38MAPK | 54.8 (discussion) | |||
| Stat-3 | leptin-ObRb | 57.2 (discussion) | |||
| VEGFR2 (P35968) | leptin-ObRb | 57.2 (discussion) | |||
| VEGFR2 (P35968) | direct recept | 48.7 (results) | |||
| Stat-3 | ObRb | 48.3 (results) | |||
| VEGFR2 (P35968) | Tyr-1175 | is required for | ObRb | 48.1 (results) |