Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4B4 / ARIP4_HUMAN
Protein Name Helicase ARIP4
Gene Name Name: RAD54L2
Synonyms:ARIP4,KIAA0809;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4B4
DAG View
PRO Name helicase ARIP4 (human)
Definition A helicase ARIP4 that is encoded in the genome of human.
Short Label hRAD54L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4B4 (RAD54L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T72 Phosphorylation PhosphoSitePlus
K115 Sumoylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K127 Sumoylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
S187 Phosphorylation HPRD   PhosphoSitePlus 17081983
S188 Phosphorylation HPRD   PhosphoSitePlus 17081983
S189 Phosphorylation HPRD   PhosphoSitePlus 17081983
S191 Phosphorylation HPRD   PhosphoSitePlus 17081983
K272 Sumoylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K469 Sumoylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
R483 Methylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
K665 Sumoylation PhosphoSitePlus
K665 Ubiquitination PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
K759 Sumoylation PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
K856 Ubiquitination PhosphoSitePlus
Y875 Phosphorylation PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus
T899 Phosphorylation PhosphoSitePlus
K901 Sumoylation PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
K912 Ubiquitination PhosphoSitePlus
K923 Ubiquitination PhosphoSitePlus
K926 Sumoylation PhosphoSitePlus
K926 Ubiquitination PhosphoSitePlus
K936 Ubiquitination PhosphoSitePlus
K943 Ubiquitination PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
S971 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1014 Sumoylation PhosphoSitePlus
K1018 Sumoylation PhosphoSitePlus
T1029 Phosphorylation PhosphoSitePlus
T1074 O-Glycosylation GlyGen 23301498, 20305658, 28657654, ...29351928
T1075 O-Glycosylation GlyGen 23301498, 20305658, 28657654, ...29351928
S1085 O-Glycosylation GlyGen 23301498, 20305658, 28657654, ...29351928
K1105 Ubiquitination PhosphoSitePlus
K1124 Ubiquitination PhosphoSitePlus
K1126 Ubiquitination PhosphoSitePlus
S1136 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation HPRD   PhosphoSitePlus 17525332
C1143 S-Nitrosylation dbSNO 26338901
S1152 Phosphorylation HPRD 18669648
S1154 Phosphorylation HPRD 18669648
S1155 Phosphorylation HPRD 18669648
S1169 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 18452278, 19651622, ...18669648, 19690332, 20068231
S1172 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 18452278, 19651622, ...18669648, 19690332, 20068231
S1177 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
Y1182 Phosphorylation HPRD 20068231
T1198 Phosphorylation HPRD 18669648
R1245 Methylation PhosphoSitePlus
R1252 Methylation PhosphoSitePlus
T1260 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163
S1272 Phosphorylation PhosphoSitePlus
R1395 Methylation PhosphoSitePlus
Y1419 Phosphorylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
R1433 Methylation PhosphoSitePlus
S1450 Phosphorylation PhosphoSitePlus
S1451 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T72 P72 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S187 I187 Biomuta DOID:3571 / liver cancer [ icgc ]
K665 N665 Biomuta DOID:363 / uterine cancer [ tcga ]
S674 L674 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S971 R971 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K1126 E1126 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S1136 L1136 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1138 F1138 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S1172 N1172 Biomuta DOID:1324 / lung cancer [ tcga ]
T1198 P1198 Biomuta DOID:1324 / lung cancer [ tcga ]