Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UI95 / MD2L2_HUMAN
Protein Name Mitotic spindle assembly checkpoint protein MAD2B
Gene Name Name: MAD2L2
Synonyms:MAD2B,REV7;
Organism Homo sapiens (Human)

PRO ID PR:Q9UI95
DAG View
PRO Name mitotic spindle assembly checkpoint protein MAD2B (human)
Definition A mitotic spindle assembly checkpoint protein MAD2B that is encoded in the genome of human.
Short Label hMAD2L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UI95 (MAD2L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K44 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K72 Q72 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K162 N162 Biomuta DOID:363 / uterine cancer [ tcga ]