Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UBS8 / RNF14_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF14
Gene Name Name: RNF14
Organism Homo sapiens (Human)

DAG View
PRO Name E3 ubiquitin-protein ligase RNF14 (human)
Definition An E3 ubiquitin-protein ligase RNF14 that is encoded in the genome of human.
Short Label hRNF14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UBS8 (RNF14) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K27 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S348 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K351 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
K394 Sumoylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S348 Phosphorylation HPRD 18691976, 18669648
Site PTM Type PTM Enzyme Score Source PMID
S222 Phosphorylation HPRD 18691976, 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S230 R230 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
S230 G230 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y379 H379 Biomuta DOID:263 / kidney cancer [ tcga ]