Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBQ5 / EIF3K_HUMAN
Protein Name Eukaryotic translation initiation factor 3 subunit K
Gene Name Name: EIF3K
Synonyms:EIF3S12;ORFNames:ARG134,HSPC029,MSTP001,PTD001;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBQ5
DAG View
PRO Name eukaryotic translation initiation factor 3 subunit K (human)
Definition A eukaryotic translation initiation factor 3 subunit K that is encoded in the genome of human.
Short Label hEIF3K
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBQ5 (EIF3K) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895, ...17322308
K13 Acetylation PhosphoSitePlus
K13 Sumoylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus   UniProt 23186163
K38 Ubiquitination PhosphoSitePlus
K52 Sumoylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S217 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S212 Phosphorylation HPRD 20068231
S216 Phosphorylation HPRD 17081983
S217 Phosphorylation HPRD 19413330, 17081983, 19664995, ...19651622, 18669648, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 S2 Biomuta DOID:3571 / liver cancer [ icgc ]
Y21 C21 Biomuta DOID:1909 / melanoma [ cosmic ]
K140 N140 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S216 F216 Biomuta DOID:4159 / skin cancer [ icgc ] DOID:1909 / melanoma [ tcga ]