iPTMnet Report for Q9P2T1 (GMPR2)
Protein Information
UniProt AC / UniProt ID | Q9P2T1 / GMPR2_HUMAN |
Protein Name | GMP reductase 2 |
Gene Name | Name: GMPR2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9P2T1 |
PRO Name | GMP reductase 2 (human) |
Definition | A GMP reductase 2 that is encoded in the genome of human. |
Short Label | hGMPR2 |
Category | organism-gene |
Q9P2T1 (GMPR2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
K13 | Acetylation | score1 | PhosphoSitePlus | |||
K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
C68 | Methylation | score1 | IEDB | 31844290 | ||
C127 | Methylation | score1 | IEDB | 31844290 | ||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
T187 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y263 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y267 | Phosphorylation | score1 | PhosphoSitePlus | |||
K277 | Acetylation | score1 | PhosphoSitePlus | |||
K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y285 | Phosphorylation | score1 | PhosphoSitePlus | |||
K291 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
K298 | Acetylation | score1 | PhosphoSitePlus | |||
K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y318 | Phosphorylation | score1 | PhosphoSitePlus | |||
C348 | S-Nitrosylation | score0 | dbSNO | 26338901 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K20 | R20 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S26 | F26 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y285 | H285 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |