iPTMnet Report for Q9P2R7 (SUCLA2)
Protein Information
UniProt AC / UniProt ID | Q9P2R7 / SUCB1_HUMAN |
Protein Name | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial precursor |
Gene Name | Name: SUCLA2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9P2R7 |
PRO Name | succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (human) |
Definition | A succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial that is encoded in the genome of human. |
Short Label | hSUCLA2 |
Category | organism-gene |
Q9P2R7 (SUCLA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 33991485 | ||
Y84 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
K88 | Acetylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
K89 | Acetylation | score1 | PhosphoSitePlus | |||
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
R106 | Methylation | score1 | PhosphoSitePlus | |||
K108 | Acetylation | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
K116 | Acetylation | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
K143 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
S281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
T295 | Phosphorylation | score1 | PhosphoSitePlus | |||
K302 | Acetylation | score1 | PhosphoSitePlus | |||
T341 | Phosphorylation | score1 | PhosphoSitePlus | |||
K368 | Acetylation | score1 | PhosphoSitePlus | |||
K417 | Ubiquitination | score1 | PhosphoSitePlus | |||
S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
T448 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | Q9P2R7 (SUCLA2) | S79 | O94925 (GLS) | unknown | eFIP | 33991485 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R106 | T106 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K120 | N120 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K216 | N216 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
S279 | C279 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S279 | F279 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K368 | R368 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
T448 | I448 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |