Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NX47 / MARH5_HUMAN
Protein Name E3 ubiquitin-protein ligase MARCH5
Gene Name Name: MARCH5
Synonyms:RNF153;
Organism Homo sapiens (Human)

PRO ID PR:Q9NX47
DAG View
PRO Name E3 ubiquitin-protein ligase MARCH5 (human)
Definition An E3 ubiquitin-protein ligase MARCH5 that is encoded in the genome of human.
Short Label hMARCH5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NX47 (MARCH5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
C46 S-Nitrosylation dbSNO 21278135
K54 Ubiquitination PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C46 F46 Biomuta DOID:3571 / liver cancer [ icgc ]
C46 Y46 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K54 N54 Biomuta DOID:3571 / liver cancer [ icgc ]