Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRD8 / DUOX2_HUMAN
Protein Name Dual oxidase 2 precursor
Gene Name Name: DUOX2
Synonyms:LNOX2,THOX2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NRD8
DAG View
PRO Name dual oxidase 2 (human)
Definition A dual oxidase 2 that is encoded in the genome of human.
Short Label hDUOX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRD8 (DUOX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y65 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
T1007 Phosphorylation PhosphoSitePlus
Y1011 Phosphorylation PhosphoSitePlus
T1012 Phosphorylation PhosphoSitePlus
Y1347 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus
S1349 Phosphorylation PhosphoSitePlus
Y1358 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y65 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y65 H65 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
Y70 C70 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
S975 F975 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1349 F1349 Biomuta DOID:1909 / melanoma [ icgc, tcga ]