Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR09 / BIRC6_HUMAN
Protein Name Baculoviral IAP repeat-containing protein 6
Gene Name Name: BIRC6
Synonyms:KIAA1289;
Organism Homo sapiens (Human)

PRO ID PR:Q9NR09
DAG View
PRO Name baculoviral IAP repeat-containing protein 6 (human)
Definition A baculoviral IAP repeat-containing protein 6 that is encoded in the genome of human.
Short Label hBIRC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR09 (BIRC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K92 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
Y301 Phosphorylation HPRD   PhosphoSitePlus 20068231
K408 Ubiquitination PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S480 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...18767875, 18452278, 19651622, 18669648, 24275569, 20068231
S482 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648
S486 Phosphorylation HPRD   PhosphoSitePlus 18452278
S488 Phosphorylation HPRD   PhosphoSitePlus 19651622
S547 Phosphorylation PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
S549 Phosphorylation phospho.ELM 18669648
T552 Phosphorylation phospho.ELM 18669648
T574 Phosphorylation PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
S577 Phosphorylation HPRD   PhosphoSitePlus 18669648
T580 Phosphorylation HPRD   PhosphoSitePlus 18669648
S581 Phosphorylation PhosphoSitePlus   UniProt 23186163
S584 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus   UniProt 23186163
S620 Phosphorylation PhosphoSitePlus
T626 Phosphorylation PhosphoSitePlus
Y633 Phosphorylation PhosphoSitePlus
S638 Phosphorylation HPRD   PhosphoSitePlus 20068231
K644 Ubiquitination PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
K845 Ubiquitination PhosphoSitePlus
S999 Phosphorylation PhosphoSitePlus
T1035 Phosphorylation PhosphoSitePlus
T1076 Phosphorylation PhosphoSitePlus
T1123 Phosphorylation PhosphoSitePlus
K1128 Ubiquitination PhosphoSitePlus
T1204 Phosphorylation PhosphoSitePlus
K1210 Ubiquitination PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
K1250 Methylation PhosphoSitePlus
K1250 Ubiquitination PhosphoSitePlus
K1255 Ubiquitination PhosphoSitePlus
S1258 Phosphorylation PhosphoSitePlus
K1265 Ubiquitination PhosphoSitePlus
K1277 Ubiquitination PhosphoSitePlus
T1281 Phosphorylation PhosphoSitePlus
S1282 Phosphorylation PhosphoSitePlus
T1284 Phosphorylation PhosphoSitePlus
T1302 Phosphorylation PhosphoSitePlus
K1380 Ubiquitination PhosphoSitePlus
K1643 Ubiquitination PhosphoSitePlus
K1648 Ubiquitination PhosphoSitePlus
T1710 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1717 Phosphorylation HPRD 17081983
K1857 Ubiquitination PhosphoSitePlus
Y1864 Phosphorylation PhosphoSitePlus
S1866 Phosphorylation PhosphoSitePlus
T1867 Phosphorylation PhosphoSitePlus
S2018 Phosphorylation PhosphoSitePlus
S2019 Phosphorylation PhosphoSitePlus
S2122 Phosphorylation PhosphoSitePlus
S2222 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2233 Ubiquitination PhosphoSitePlus
K2239 Ubiquitination PhosphoSitePlus
K2246 Ubiquitination PhosphoSitePlus
K2250 Ubiquitination PhosphoSitePlus
K2258 Ubiquitination PhosphoSitePlus
K2265 Ubiquitination PhosphoSitePlus
K2270 Ubiquitination PhosphoSitePlus
K2277 Ubiquitination PhosphoSitePlus
K2287 Ubiquitination PhosphoSitePlus
T2295 Phosphorylation PhosphoSitePlus
T2305 Phosphorylation PhosphoSitePlus
T2309 Phosphorylation PhosphoSitePlus
K2311 Ubiquitination PhosphoSitePlus
K2511 Ubiquitination PhosphoSitePlus
T2530 Phosphorylation PhosphoSitePlus
K2907 Ubiquitination PhosphoSitePlus
S2955 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3139 Ubiquitination PhosphoSitePlus
S3143 Phosphorylation PhosphoSitePlus
K3146 Ubiquitination PhosphoSitePlus
S3289 Phosphorylation PhosphoSitePlus
K3395 Ubiquitination PhosphoSitePlus
S3578 Phosphorylation PhosphoSitePlus
K3585 Ubiquitination PhosphoSitePlus
S3591 Phosphorylation PhosphoSitePlus
K3597 Ubiquitination PhosphoSitePlus
S3629 Phosphorylation PhosphoSitePlus
S3633 Phosphorylation PhosphoSitePlus
S3649 Phosphorylation HPRD   PhosphoSitePlus 20058876
S3660 Phosphorylation HPRD   PhosphoSitePlus 20058876
K3675 Methylation PhosphoSitePlus
T3679 Phosphorylation PhosphoSitePlus
S3742 Phosphorylation PhosphoSitePlus
K3834 Ubiquitination PhosphoSitePlus
K3854 Ubiquitination PhosphoSitePlus
K3882 Ubiquitination PhosphoSitePlus
Y3912 Phosphorylation PhosphoSitePlus
S3913 Phosphorylation PhosphoSitePlus
T3931 Phosphorylation PhosphoSitePlus   UniProt 23186163
S3937 Phosphorylation PhosphoSitePlus
K3946 Ubiquitination PhosphoSitePlus
S4010 Phosphorylation PhosphoSitePlus
S4019 Phosphorylation PhosphoSitePlus
K4020 Ubiquitination PhosphoSitePlus
T4021 Phosphorylation PhosphoSitePlus
S4023 Phosphorylation PhosphoSitePlus   UniProt 23186163
K4110 Ubiquitination PhosphoSitePlus
Y4130 Phosphorylation PhosphoSitePlus
K4176 Ubiquitination PhosphoSitePlus
T4227 Phosphorylation PhosphoSitePlus
Y4288 Phosphorylation PhosphoSitePlus
S4299 Phosphorylation PhosphoSitePlus
K4312 Ubiquitination PhosphoSitePlus
C4443 S-Nitrosylation dbSNO 26338901
K4463 Ubiquitination PhosphoSitePlus
Y4489 Phosphorylation PhosphoSitePlus
K4522 Acetylation PhosphoSitePlus
S4523 Phosphorylation HPRD   PhosphoSitePlus 18510355
K4527 Methylation PhosphoSitePlus
Y4528 Phosphorylation PhosphoSitePlus
K4534 Methylation PhosphoSitePlus
S4561 Phosphorylation PhosphoSitePlus
S4571 Phosphorylation HPRD   PhosphoSitePlus 20068231
S4714 Phosphorylation PhosphoSitePlus
T4717 Phosphorylation PhosphoSitePlus
S4724 Phosphorylation PhosphoSitePlus
K4810 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K92 R92 Biomuta DOID:1324 / lung cancer [ icgc ]
K212 E212 Biomuta DOID:3070 / malignant glioma [ tcga ]
K408 N408 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S462 I462 Biomuta DOID:1324 / lung cancer [ cosmic ]
S462 R462 Biomuta DOID:1324 / lung cancer [ cosmic ]
S464 L464 Biomuta DOID:1324 / lung cancer [ tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
S480 L480 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S482 N482 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
T574 K574 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S581 L581 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S584 C584 Biomuta DOID:263 / kidney cancer [ cosmic ]
S620 F620 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T626 A626 Biomuta DOID:3571 / liver cancer [ icgc ]
K644 N644 Biomuta DOID:363 / uterine cancer [ tcga ]
K845 Q845 Biomuta DOID:3070 / malignant glioma [ tcga ]
S999 * Biomuta DOID:1612 / breast cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K1210 N1210 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K1277 N1277 Biomuta DOID:3571 / liver cancer [ icgc ]
T1710 S1710 Biomuta DOID:3571 / liver cancer [ tcga ]
K1857 N1857 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1866 R1866 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S2122 C2122 Biomuta DOID:3571 / liver cancer [ tcga ]
K2511 N2511 Biomuta DOID:3571 / liver cancer [ icgc ]
T2530 S2530 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K2907 Q2907 Biomuta DOID:363 / uterine cancer [ tcga ]
S3289 G3289 Biomuta DOID:363 / uterine cancer [ tcga ]
S3578 P3578 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S3633 Y3633 Biomuta DOID:363 / uterine cancer [ tcga ]
S3633 A3633 Biomuta DOID:363 / uterine cancer [ tcga ]
K3675 E3675 Biomuta DOID:363 / uterine cancer [ tcga ]
Y3912 C3912 Biomuta DOID:363 / uterine cancer [ tcga ]
S4010 P4010 Biomuta DOID:263 / kidney cancer [ tcga ]
S4023 Y4023 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
Y4288 F4288 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S4299 F4299 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S4299 C4299 Biomuta DOID:1324 / lung cancer [ tcga ]
C4443 F4443 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K4534 N4534 Biomuta DOID:363 / uterine cancer [ tcga ]
S4561 F4561 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S4724 F4724 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]