Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQ87 / HEYL_HUMAN
Protein Name Hairy/enhancer-of-split related with YRPW motif-like protein
Gene Name Name: HEYL
Synonyms:BHLHB33,HRT3;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQ87
DAG View
PRO Name hairy/enhancer-of-split related with YRPW motif-like protein (human)
Definition A hairy/enhancer-of-split related with YRPW motif-like protein that is encoded in the genome of human.
Short Label hHEYL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQ87 (HEYL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Acetylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K53 E53 Biomuta DOID:9256 / colorectal cancer [ tcga ]
R240 L240 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R240 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T256 N256 Biomuta DOID:3571 / liver cancer [ icgc ]