Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NPC4 / A4GAT_HUMAN
Protein Name Lactosylceramide 4-alpha-galactosyltransferase
Gene Name Name: A4GALT
Organism Homo sapiens (Human)

DAG View
PRO Name lactosylceramide 4-alpha-galactosyltransferase (human)
Definition A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of human.
Short Label hA4GALT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NPC4 (A4GALT) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
T65 O-Glycosylation GlyGen 30459171
T68 O-Glycosylation GlyGen 30459171
T84 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
N121 N-Glycosylation GlyGen 23090970, 24190977
R179 Methylation PhosphoSitePlus
N203 N-Glycosylation GlyGen 23090970, 24190977
S321 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T65 K65 Biomuta DOID:3571 / liver cancer [ icgc ]
S85 L85 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S321 R321 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:3571 / liver cancer [ icgc ]